ID   A0A1I6X2E6_9GAMM        Unreviewed;       630 AA.
AC   A0A1I6X2E6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=TrkA-C domain-containing protein {ECO:0000313|EMBL:SFT32071.1};
GN   ORFNames=SAMN04487956_10110 {ECO:0000313|EMBL:SFT32071.1};
OS   Halomonas saccharevitans.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=416872 {ECO:0000313|EMBL:SFT32071.1, ECO:0000313|Proteomes:UP000199594};
RN   [1] {ECO:0000313|EMBL:SFT32071.1, ECO:0000313|Proteomes:UP000199594}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.6493 {ECO:0000313|EMBL:SFT32071.1,
RC   ECO:0000313|Proteomes:UP000199594};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FPAQ01000001; SFT32071.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6X2E6; -.
DR   OrthoDB; 9809303at2; -.
DR   Proteomes; UP000199594; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR   InterPro; IPR004680; Cit_transptr-like_dom.
DR   InterPro; IPR031312; Na/sul_symport_CS.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   PANTHER; PTHR43652; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR   PANTHER; PTHR43652:SF2; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR   Pfam; PF03600; CitMHS; 1.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS01271; NA_SULFATE; 1.
DR   PROSITE; PS51202; RCK_C; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        23..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        48..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        171..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        437..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        460..478
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        485..503
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        523..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        570..587
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        608..628
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          206..290
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   DOMAIN          336..423
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   REGION          288..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..325
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   630 AA;  66736 MW;  1C3B7F98A5D18932 CRC64;
     MSDSTQVFMV LGATLAAFVW GRFRYDLVAL GALLASVLLG LVPTDEAFYG FGHPAVITVA
     AVLVLSRGFE RSGLVDLIAE QALRVGDRLI LQMLVLSGTV LVLSGVMNNV GALALMLPVA
     IRMAREHDSP PSLLLMPLAF GSLLGGLTTL IGTPPNIIIS SYRHEAVGES FGMFSFFPVG
     ASVALVGLAF IVLVGWRLVP QRAGKASTEE MFDTAHYLVE LRVPEDGKAV GWTLRDLHQA
     LEETIPVLAV VRGDTRHAGH AFHGTLGEGD ILLVEAGPEE MKLIEDKAGL VVGPEPPPDD
     EAQDAETRER EASAAPRKAQ QGDESQDDEP QGEEEEEAQR SAVDTEGLQL VEAVVRNDSM
     MIHRTVTQLR LHNQFGLHLV AVARDGGRLN QRLRDIRFRA GDVLLLQGGE GEIGESLTTL
     GCLPLASRNL TLGRPRMLAV SVAIFAVAVI AMVLDLVPSS VALTAAALVS LMVGVLSLRE
     GYQAIDGPVI VLLGAMIPVG QALETSGGAS LIAEILLAMG REWPVVATLV GLFLICTLLS
     NVVNNAAAAL LMAPIAASLA EGFGVSLDPF LMVVAISASC AFLTPIGHQS NTLVMGPGGY
     RFGDYWKLGL PLTLVVMAVA IPLILIVWPL
//