ID   A0A1I6X412_9FIRM        Unreviewed;       470 AA.
AC   A0A1I6X412;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Broad specificity phosphatase PhoE {ECO:0000313|EMBL:SFT32926.1};
GN   ORFNames=SAMN02910301_0348 {ECO:0000313|EMBL:SFT32926.1};
OS   Lachnospiraceae bacterium XBD2001.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1520820 {ECO:0000313|EMBL:SFT32926.1, ECO:0000313|Proteomes:UP000199425};
RN   [1] {ECO:0000313|EMBL:SFT32926.1, ECO:0000313|Proteomes:UP000199425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XBD2001 {ECO:0000313|EMBL:SFT32926.1,
RC   ECO:0000313|Proteomes:UP000199425};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; FPAN01000002; SFT32926.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6X412; -.
DR   STRING; 1520820.SAMN02910301_0348; -.
DR   OrthoDB; 1829094at2; -.
DR   Proteomes; UP000199425; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd07067; HP_PGM_like; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR   InterPro; IPR013078; His_Pase_superF_clade-1.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   PANTHER; PTHR46517; FRUCTOSE-2,6-BISPHOSPHATASE TIGAR; 1.
DR   PANTHER; PTHR46517:SF1; FRUCTOSE-2,6-BISPHOSPHATASE TIGAR; 1.
DR   Pfam; PF00300; His_Phos_1; 1.
DR   SMART; SM00855; PGAM; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199425};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        43..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   BINDING         259..266
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT   BINDING         309
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ   SEQUENCE   470 AA;  52442 MW;  98CA9CC9E5AE559C CRC64;
     MLESLKLLHN VLWSSTLMMG LCLASIGYLI YRGIKKQESV TMRITLLFTV MTGILVCMNP
     ILSKLLTRIS GDKYTFIRFT WLLPVFALMA YAATRIILDF EGRKRFVACI LVFGLILCAG
     RPWPSVYLKA ENIYKVENSL KDACDAIRTD CAHERPNVTV YIPSNNIYED GSAANMRYFG
     VRQYAPEFVL DYMTVADSQL QEENFTFAGN LWNIGEYVIC PKNEVLQREL QRIGYEVLHE
     SDDLAVLKNT VRMTIIFVRH GQTEANVNNI AVGLTESPLT SVGIEQAKAA GHSLKGVTID
     AVYSSHLQRA TETAQYVLQE SGNEGVNMNL SVYLSDIGWG DAEGMSMDEI RQTYGIEPNI
     HTVFGPVEEE DYVGPIPNIY NLHDYVHNFH MNVQGAITNS YVSGMNGGTI LITGHSAAAQ
     WMRYILPTTE VPDGLDNASV SILHYDCGAW SAETLNNTDY EEVAEIAGTL
//