ID   A0A1I6YC57_9BACT        Unreviewed;       450 AA.
AC   A0A1I6YC57;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SFT47814.1};
GN   ORFNames=SAMN04489724_0920 {ECO:0000313|EMBL:SFT47814.1};
OS   Algoriphagus locisalis.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Algoriphagus.
OX   NCBI_TaxID=305507 {ECO:0000313|EMBL:SFT47814.1, ECO:0000313|Proteomes:UP000199673};
RN   [1] {ECO:0000313|EMBL:SFT47814.1, ECO:0000313|Proteomes:UP000199673}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23445 {ECO:0000313|EMBL:SFT47814.1,
RC   ECO:0000313|Proteomes:UP000199673};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FPBF01000001; SFT47814.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6YC57; -.
DR   STRING; 305507.SAMN04489724_0920; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000199673; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        95..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        145..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        187..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        243..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        301..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        353..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        392..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        416..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   450 AA;  48447 MW;  ACF6E8FAAB816594 CRC64;
     MGEYIISFAN WIWGTPMLVI LMGGGLLLLV HSGFVPFRKI GHAIGLLRGK YDDSLLPGQI
     TSFQALSSAI AATVGLGNIS GVAIAINMGG PGAIFWMWVS AFVGMATKFY TCSLAIMFRG
     KDSEGQIQGG PMYVIEEGMG KKWKFLSIIF CTAGVLGLLA IFQANQLTAV LRTVILEPAG
     LDEGDKTRWI IGITMMVLVA IVILGGIKRI AGVASKLVPF MVGLYFVTVI IIVFKYIGDV
     PEMLLKIVTD AFTGEAMAGG AVGAVIVIGA RRAAFSNEAG IGTAPMVHGA SKNNEPIREG
     LIAMLGPFID TIVVCTLTAL VIMLTGVWES TEKDGVRLTL AAFDLALPYY GRYLLMVAVL
     VFALSTMFTY SYYGHKCFGY LFGAKRADYY NYFYLITIVA GAVASLDVVI SLVDGMYAIM
     AVPTMISTIY LAPKVRVAMK DYFERMKKAA
//