ID A0A1I6ZQB3_9FIRM Unreviewed; 225 AA.
AC A0A1I6ZQB3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases {ECO:0000313|EMBL:SFT64820.1};
GN ORFNames=SAMN02910301_0037 {ECO:0000313|EMBL:SFT64820.1};
OS Lachnospiraceae bacterium XBD2001.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1520820 {ECO:0000313|EMBL:SFT64820.1, ECO:0000313|Proteomes:UP000199425};
RN [1] {ECO:0000313|EMBL:SFT64820.1, ECO:0000313|Proteomes:UP000199425}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XBD2001 {ECO:0000313|EMBL:SFT64820.1,
RC ECO:0000313|Proteomes:UP000199425};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FPAN01000012; SFT64820.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6ZQB3; -.
DR STRING; 1520820.SAMN02910301_0037; -.
DR OrthoDB; 1706474at2; -.
DR Proteomes; UP000199425; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF78; LISTERIOLYSIN REGULATORY PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SFT64820.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199425};
KW Transferase {ECO:0000313|EMBL:SFT64820.1}.
FT DOMAIN 11..130
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 145..218
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 225 AA; 25766 MW; A1B16A461E4E7D53 CRC64;
MNSEKRVERG LLNLLSEKSR KELLDAGKVK TLKKGEILFA EREEVKCMYI ILDGFVALYR
NSRYGEIKII FICTNGEVLN EVVLQDKKTS ICTKALADTQ LLCVHRSEIY KLMADNTELS
REIFDSLARK TRRLYHQVGN ANGTYPIEKR LAAKIWKLAR DYGNSTPEGV QISFELTVTF
LANMLGAKRE TISRIISSWK KDEIVIHENG FLTVIDMKSL KEISQ
//
