ID   A0A1I7BH38_9MICC        Unreviewed;       326 AA.
AC   A0A1I7BH38;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Membrane protein insertase YidC {ECO:0000256|ARBA:ARBA00015325};
DE   AltName: Full=Foldase YidC {ECO:0000256|ARBA:ARBA00033342};
DE   AltName: Full=Membrane integrase YidC {ECO:0000256|ARBA:ARBA00033245};
DE   AltName: Full=Membrane protein YidC {ECO:0000256|ARBA:ARBA00031538};
GN   ORFNames=SAMN04487915_104132 {ECO:0000313|EMBL:SFT86431.1};
OS   Arthrobacter sp. ov118.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=1761747 {ECO:0000313|EMBL:SFT86431.1, ECO:0000313|Proteomes:UP000199457};
RN   [1] {ECO:0000313|EMBL:SFT86431.1, ECO:0000313|Proteomes:UP000199457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OV118 {ECO:0000313|EMBL:SFT86431.1,
RC   ECO:0000313|Proteomes:UP000199457};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as well
CC       as at least some lipoproteins. Aids folding of multispanning membrane
CC       proteins. {ECO:0000256|ARBA:ARBA00025034}.
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent integral
CC       membrane proteins during membrane integration.
CC       {ECO:0000256|ARBA:ARBA00026028}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00010527}.
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DR   EMBL; FPAY01000004; SFT86431.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I7BH38; -.
DR   STRING; 1761747.SAMN04487915_104132; -.
DR   OrthoDB; 9780552at2; -.
DR   Proteomes; UP000199457; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd20070; 5TM_YidC_Alb3; 1.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR028055; YidC/Oxa/ALB_C.
DR   InterPro; IPR047196; YidC_ALB_C.
DR   NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR   PANTHER; PTHR12428:SF65; INNER MEMBRANE PROTEIN ALBINO3, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR12428; OXA1; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003945};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        109..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        224..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          39..261
FT                   /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02096"
SQ   SEQUENCE   326 AA;  35607 MW;  A1B12850B0293BBE CRC64;
     MDFFETIMFP FKWLVSAIMV GFHDGLSAIG MSPANGWTWT LSIIGLVLVI RAALIPVFVK
     QIKAQRGMQL LQPDLKKLQD KYKGKTDQLS RQAMAQEQMA LYKHHGTNPF SACLPMLIQM
     PFFFALFQVL SGITASAQAG KGIGAMSAEQ VKQFDESTIF GAPLSASLLH GGAGGNEAAV
     WILSILMILA MTASQFITQK QIMAKNMSEE ALASPFMRQQ KMMLYILPVV FGVGGINFPI
     GVLIYWTTTN LWTMGQQFFV IRRMPTPGSP AAKALAERRA AKGLPALPLL GGKKVDAEAA
     EASAAAAAVE AKTQRIQPQR KNRKRK
//