ID   A0A1I7ECM6_9RHOB        Unreviewed;      1027 AA.
AC   A0A1I7ECM6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:SFU21716.1};
GN   ORFNames=SAMN05216236_1672 {ECO:0000313|EMBL:SFU21716.1};
OS   Sedimentitalea nanhaiensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Sedimentitalea.
OX   NCBI_TaxID=999627 {ECO:0000313|EMBL:SFU21716.1, ECO:0000313|Proteomes:UP000182466};
RN   [1] {ECO:0000313|EMBL:SFU21716.1, ECO:0000313|Proteomes:UP000182466}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.10959 {ECO:0000313|EMBL:SFU21716.1,
RC   ECO:0000313|Proteomes:UP000182466};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FPAW01000067; SFU21716.1; -; Genomic_DNA.
DR   RefSeq; WP_027263663.1; NZ_FPAW01000067.1.
DR   AlphaFoldDB; A0A1I7ECM6; -.
DR   STRING; 999627.SAMN05216236_1672; -.
DR   eggNOG; COG0841; Bacteria.
DR   OrthoDB; 9798415at2; -.
DR   Proteomes; UP000182466; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF18; CATION EFFLUX SYSTEM PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000182466};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        392..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        462..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        522..542
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        883..903
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        909..930
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        958..979
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        985..1007
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1027 AA;  110718 MW;  149B7E28349E6990 CRC64;
     MAFSISGASI QRPVAVWLLI LFCLLGGYWG LNTVGRLEDP SFTLKTALVF VPYPGATAVE
     VEEEVSDVIE NALQQMKQLD RVESKSMPGM AQITVEIEGT YGPDEIPQVW DEMRLRIRDV
     EGELPEGARA PIVNDDFGDV YGMFYAVKTE GLSPREERDL ATKLRLGLVT VDGVAKVEVQ
     GLTEEVITIS IPSARLTELG LPPNQVLSVL NDENLVFDNG EITEGPARIG LSVPPGYVTP
     EGIEELRLGA AGEVGQVAIH DIARVARDEA EQPSQIIRQN GTAAFTLGVS ALTNRNVVEV
     GAAAAARLEK LKAELPEGVE ITPIYEQHVV VDQAVSSFLL SLAMSVAIVV GALILTMGWR
     AGLVVGATLG LTVFVTLFFM SVFGIAMERI SLGALIIAMG MLVDNAIVIT EGMVIGMARG
     KSAEKAAAET ESSTSIPLLG ATVIGIMAFS GIGLSPDATG EFLFSLFAVI TISLLMSWIL
     AVTVTPYLGK LLLKAPKNTS DDPYKGAFYG IYRGMLWLVL RARVLVVLII VGITVVSVMA
     FGQVKQAFFP ASNTPLFYVE FQMPQGTDIN VTDREMRRLE QMFLAEEGVT DVTTLVGRGA
     SRFMLTYSPE QADASYGQLI VRVADAEAIP AMANRLNRDL PAAFPNALVR VEELVFGPPS
     GADVAVRFSG ADPVILRQLA DDATRIYAAA GTITNSRTNW RQREILIEPI VDESRMRLAG
     TSRSAISDTV RYGTSGLRVG ELREGDEVIP IHLRLPANER DGIDRVRDLS AWSDGAGAYV
     PMANLVERFE PRLVEALIHR RNRERTITAL GGARGDLTAD EAFKSVRTEI EALPPPEGYS
     MEWGGQYESS TDAQTSLGKQ LPLSFLVMLT ISILMFNKVR QPLILWLVVP MSVTGMVLGL
     LFTGLPFTFT ALLGFLSLSG MLMKNAIVLV EEIDVQRADG VPDYKAVIDG SVSRLRPVVL
     AAGTTIFGMI PLLPDAFFAS MAVTIMGGLA FASVLTLVAV PVLYALLFRI RPPKDESADS
     KTGTASG
//