ID   A0A1I7F4S0_9BURK        Unreviewed;       388 AA.
AC   A0A1I7F4S0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Glutathione-independent formaldehyde dehydrogenase {ECO:0000313|EMBL:SFU31160.1};
GN   ORFNames=SAMN05216552_1001375 {ECO:0000313|EMBL:SFU31160.1};
OS   Pseudoduganella namucuonensis.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Telluria group; Pseudoduganella.
OX   NCBI_TaxID=1035707 {ECO:0000313|EMBL:SFU31160.1, ECO:0000313|Proteomes:UP000199391};
RN   [1] {ECO:0000313|Proteomes:UP000199391}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.11014 {ECO:0000313|Proteomes:UP000199391};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; FPBO01000001; SFU31160.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I7F4S0; -.
DR   STRING; 1035707.SAMN05216552_1001375; -.
DR   OrthoDB; 9773078at2; -.
DR   Proteomes; UP000199391; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199391};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          26..152
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          197..277
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   388 AA;  41692 MW;  CFB5B5D54C1F9A17 CRC64;
     MRALCYHSAH EVSVDTVPDP VIQEADDIII QITATAICGS DLHLYRGKVP GMHEGDVLGH
     EFMGIVVEAG LSVTKLRKGD RVVVPFVIAC GSCYFCDHQL FSACETTNPD RGTIMNKKSL
     RSGAALFGFS HFYGGMPGGQ AEYVRVPKAN VGPIKIPDAL PDEKVLFLSD ILPTGYQAVL
     NTGVGKGGSL AIYGGGPVGQ MAAATARMLG VERIFMVDHH PYRLEFARST YGIIPVNFDE
     VDAAEYIIEN TGSRGVDGVV DAVGFEAKGS AVETVMTNLK LEGSSGAALR QCIAACRRGG
     TVSVPGLYAG FIHGFLFGDL FEKGLTIKAG QTHVQRFMPE LLEFIGEGKL HPDVIISHRL
     PLEDAALGYK MFDKKEDNCR KVILRPGS
//