ID   A0A1I7FAV1_9FIRM        Unreviewed;       347 AA.
AC   A0A1I7FAV1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Regulator of protease activity HflC, stomatin/prohibitin superfamily {ECO:0000313|EMBL:SFU33271.1};
GN   ORFNames=SAMN05216508_10216 {ECO:0000313|EMBL:SFU33271.1};
OS   Eubacterium pyruvativorans.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=155865 {ECO:0000313|EMBL:SFU33271.1, ECO:0000313|Proteomes:UP000198817};
RN   [1] {ECO:0000313|EMBL:SFU33271.1, ECO:0000313|Proteomes:UP000198817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KHGC13 {ECO:0000313|EMBL:SFU33271.1,
RC   ECO:0000313|Proteomes:UP000198817};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family.
CC       {ECO:0000256|ARBA:ARBA00008164}.
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DR   EMBL; FPBT01000002; SFU33271.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I7FAV1; -.
DR   STRING; 155865.SAMN05216515_101151; -.
DR   OrthoDB; 9809197at2; -.
DR   Proteomes; UP000198817; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd08829; SPFH_paraslipin; 1.
DR   Gene3D; 3.30.479.30; Band 7 domain; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR018080; Band_7/stomatin-like_CS.
DR   InterPro; IPR001972; Stomatin_HflK_fam.
DR   PANTHER; PTHR43327:SF63; PROTEIN QMCA; 1.
DR   PANTHER; PTHR43327; STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   PRINTS; PR00721; STOMATIN.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; Band 7/SPFH domain; 1.
DR   PROSITE; PS01270; BAND_7; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:SFU33271.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Protease {ECO:0000313|EMBL:SFU33271.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198817};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          17..175
FT                   /note="Band 7"
FT                   /evidence="ECO:0000259|SMART:SM00244"
FT   REGION          301..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..347
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   347 AA;  38146 MW;  0F8BD5A07F48A80A CRC64;
     MLSIIIPLVI IIALIAANVR IVPQAQTYVI EFLGKYKATW NAGLHVKIPF LERIVKKISL
     KEQVLDFPPQ PVITKDNVTM QIDSVVFCKV IDPKLYTYGV ESPITGLQNL SATTLRNIIG
     DMELDQTLTS RDEINRRMEA ILDEATDPWG IRVTRVEIRN INPPKEIEEV MTKQMRAERE
     RRQTVLEAQA HQEAVVSRAE GDKKAKILSA EADRDAQIAM AEGRARSIQL IYQAEADGLR
     ALREANIDEA VLKLKGIEAL KDVSDGRATK IYMPSDMTNV IASLGVAGEA LGIGDATAID
     KAPKKQPPLA PDPCITDTTG KGGVDASITT RTINRDISQA GSQQESE
//