ID   A0A1I7GXP2_9FIRM        Unreviewed;       593 AA.
AC   A0A1I7GXP2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Anthranilate synthase component 1 {ECO:0000256|ARBA:ARBA00020653};
GN   ORFNames=SAMN05216508_1105 {ECO:0000313|EMBL:SFU53217.1};
OS   Eubacterium pyruvativorans.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=155865 {ECO:0000313|EMBL:SFU53217.1, ECO:0000313|Proteomes:UP000198817};
RN   [1] {ECO:0000313|EMBL:SFU53217.1, ECO:0000313|Proteomes:UP000198817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KHGC13 {ECO:0000313|EMBL:SFU53217.1,
RC   ECO:0000313|Proteomes:UP000198817};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SUBUNIT: Heterotetramer consisting of two non-identical subunits: a
CC       beta subunit (TrpG) and a large alpha subunit (TrpE).
CC       {ECO:0000256|ARBA:ARBA00011575}.
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DR   EMBL; FPBT01000010; SFU53217.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I7GXP2; -.
DR   STRING; 155865.SAMN05216515_11147; -.
DR   Proteomes; UP000198817; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR019999; Anth_synth_I-like.
DR   InterPro; IPR006805; Anth_synth_I_N.
DR   InterPro; IPR015890; Chorismate_C.
DR   PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR   PANTHER; PTHR11236:SF48; ISOCHORISMATE SYNTHASE MENF; 1.
DR   Pfam; PF04715; Anth_synt_I_N; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   PRINTS; PR00095; ANTSNTHASEI.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   4: Predicted;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198817}.
FT   DOMAIN          135..272
FT                   /note="Anthranilate synthase component I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04715"
FT   DOMAIN          324..577
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
SQ   SEQUENCE   593 AA;  66449 MW;  90ECD24E5F63E64B CRC64;
     MLLQRACGGE MQAEIQAVEY GSLRARRKAP GDPCRVFRDV KAYVSCQEYV GIPQRAQPAK
     QGGIADDRIH SSLTDPERIC QGLFLSAAPA PPDCAGVFQK GDRLMKITPS QEEIRRLAGI
     GEYDVAPVMG EILSDVATPV QVMRILMNVS AHCFMLESAE DNEQWGRYSF LGFEPKRALC
     CADGTLKIDD VTIEQADPRK YIRQILQKNR APKIPGMPPF TGGLVGYFSY DYLKYSEPTL
     RLDAEDTEGF QDVDLMLFDR VICFDNYRQK ILLIVNMPLG EDLKASYNKA VLEIRHLREL
     ILTGTPKKDI SGRMTSEIRP FFTREQYCEM VEKAKHGIRE GDIFQIVLSN RLEADFQGSL
     FPAYRVLRTL NPSPYMLYFS GSDMEVAGSS PETLVKLQDG TLHTFPLAGT RPRGKTKEED
     DRLEKELLED PKELAEHNML VDLGRNDIGK LSRFGTVEVE RYHTIQKYSH VMHIGSTIRG
     EIRDDRDALD AIDAVLPAGT LSGAPKLRAC QMINDLEQNK RGIYGGAIGY IDFTGNLDCC
     IAIRIAYKKN NKVFIRSGAG IVSDSVPEKE YQECLNKAAA VVTALKEAEE EEE
//