ID   A0A1I7J2Y4_9FIRM        Unreviewed;       249 AA.
AC   A0A1I7J2Y4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=23S rRNA (Guanosine2251-2'-O)-methyltransferase {ECO:0000313|EMBL:SFU79494.1};
GN   ORFNames=SAMN05216540_11076 {ECO:0000313|EMBL:SFU79494.1};
OS   Butyrivibrio sp. M55.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Butyrivibrio.
OX   NCBI_TaxID=1855323 {ECO:0000313|EMBL:SFU79494.1, ECO:0000313|Proteomes:UP000199511};
RN   [1] {ECO:0000313|EMBL:SFU79494.1, ECO:0000313|Proteomes:UP000199511}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M55 {ECO:0000313|EMBL:SFU79494.1,
RC   ECO:0000313|Proteomes:UP000199511};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FPCD01000010; SFU79494.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I7J2Y4; -.
DR   Proteomes; UP000199511; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd18103; SpoU-like_RlmB; 1.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR   InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR013123; SpoU_subst-bd.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR   PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR   PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   Pfam; PF08032; SpoU_sub_bind; 1.
DR   SMART; SM00967; SpoU_sub_bind; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
DR   SUPFAM; SSF55315; L30e-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SFU79494.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199511};
KW   Transferase {ECO:0000313|EMBL:SFU79494.1}.
FT   DOMAIN          9..85
FT                   /note="RNA 2-O ribose methyltransferase substrate binding"
FT                   /evidence="ECO:0000259|SMART:SM00967"
SQ   SEQUENCE   249 AA;  26761 MW;  9A1A2E528C99753F CRC64;
     MEENFESRII EGRNAVLEAF RAGKTIDRLF VLDGCKDGPV QTIMREAKKH KDTVVSFVKK
     ERLDQLSETG KHQGVIAYAA SYEYAEVEDI LAKAAAKNED PFVIILDGIE DPHNLGAIIR
     TANLAGAHGV IIPKHRAVGL TATVAKASAG ALNYTPVAKV TNIVKTIEEL KDKGLWFACA
     DMGGTEMYKL NLKGPIGIVI GNEGSGVSRL VKENCDMIAS IPMKGDIDSL NASVAAGVLA
     FEVVRQRLG
//