ID A0A1I7JUG6_9FIRM Unreviewed; 664 AA.
AC A0A1I7JUG6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=DNA polymerase {ECO:0000313|EMBL:SFU88795.1};
GN ORFNames=SAMN05216540_11735 {ECO:0000313|EMBL:SFU88795.1};
OS Butyrivibrio sp. M55.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio.
OX NCBI_TaxID=1855323 {ECO:0000313|EMBL:SFU88795.1, ECO:0000313|Proteomes:UP000199511};
RN [1] {ECO:0000313|EMBL:SFU88795.1, ECO:0000313|Proteomes:UP000199511}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M55 {ECO:0000313|EMBL:SFU88795.1,
RC ECO:0000313|Proteomes:UP000199511};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase type-A family.
CC {ECO:0000256|ARBA:ARBA00007705}.
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DR EMBL; FPCD01000017; SFU88795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I7JUG6; -.
DR Proteomes; UP000199511; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR CDD; cd08642; DNA_pol_A_pol_I_A; 1.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF62; DNA POLYMERASE THETA; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000199511}.
FT DOMAIN 388..630
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 664 AA; 74985 MW; 27FBE67126CA4F8C CRC64;
MREMSIDLET YSDIDISKCG AYKYAESENF EILLFGVSVD GSPVTVYDLA CGDTIPDEIL
AALSDENVTK WAFNAAFERI CLSNWLKRHR PEYFTGYSIP EDPAGKYLNP ASWKCSMIWS
AYMGLPLSLE GVGAVLKLHD QKLKEGKDLI RYFCSPCKPT KANGGRTRNL PEHDSEKWEL
FKKYNQRDVE VEMSIQKRLA KFPVPEQIWD EYHLDQEIND RGIMLDMTVV ENAIAFDEKS
KSTLMLQMQN LTGLDNPNSV VQMKEWLSDN GIEMDSLGKK EVAGFVKSSD GNTNGNITEA
LKLHLQLAKS SVKKYQAMQN AVCKDGRAHG MFQFYGANRS GRWAGRLIQL QNLPQNHMPD
LTEARAIVKA GDYDTLQLLY DDIPDTLSQL IRTAFVPRSG YKFIVSDFSA IEARVLAYLA
GETWRSKVFA EGKDIYCASA SQMFGVPVEK HGINGHLRQK GKIAELALGY GGSVGALKSM
GALEMGLTEE ELQPLVNSWR NSNPMITAFW WDIDRAVKTT ITQRIQTEVR GIKFFYKSGM
LFIKLPSGRL LSYVKPRIGE NQFGGESVTY EGVGSTKKWE RIESYGPKFV ENIVQAVSRD
ILCNAMKTLR HCFIVGHVHD ELIIECDPRV DLKSVCEQMS RSPAWMPDIL LRADGYETSF
YKKD
//
