ID   A0A1I7KBR1_9BACL        Unreviewed;       302 AA.
AC   A0A1I7KBR1;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Bifunctional non-homologous end joining protein LigD {ECO:0000313|EMBL:SFU94855.1};
GN   ORFNames=SAMN05421543_1159 {ECO:0000313|EMBL:SFU94855.1};
OS   Alicyclobacillus macrosporangiidus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC   Alicyclobacillus.
OX   NCBI_TaxID=392015 {ECO:0000313|EMBL:SFU94855.1, ECO:0000313|Proteomes:UP000183508};
RN   [1] {ECO:0000313|Proteomes:UP000183508}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17980 {ECO:0000313|Proteomes:UP000183508};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; FPBV01000015; SFU94855.1; -; Genomic_DNA.
DR   RefSeq; WP_074953880.1; NZ_FPBV01000015.1.
DR   AlphaFoldDB; A0A1I7KBR1; -.
DR   STRING; 392015.SAMN05421543_1159; -.
DR   OrthoDB; 5503604at2; -.
DR   Proteomes; UP000183508; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd07906; Adenylation_DNA_ligase_LigD_LigC; 1.
DR   Gene3D; 3.30.1490.70; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR45674:SF15; DNA LIGASE (ATP); 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS00333; DNA_LIGASE_A2; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000183508}.
FT   DOMAIN          105..195
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
SQ   SEQUENCE   302 AA;  35448 MW;  171A6EAFC9BEEDF7 CRC64;
     MLFTPINPML PNMHMEAFDD PNYIFEPKWD GWRILLHKQG DRVEGFTRNG RIVTDRFPEL
     REVASAIRAY SAVLDCEGIC LRDGRSVFDD FQYRGRIQDP RRIHRAMQTH PVTFVAFDVL
     YTDRSHMNEP LLYRKQRLFD LVQSSHILTP TMFVDGAGIK MKRLTEQRNW EGIVAKRKDS
     LYIPDTRTTN WLKIKNWKEI DAVILGYRRE PQFGLVVGLH FPTVRNKPVA VVEYGFKAEE
     KTAFLEVAKE IHTAKDRDVQ WIAPVLCCKI QYLERTERHH LRTVAFRGFV PGKDPAECRW
     IS
//