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Database: UniProt
Entry: A0A1I7L680_9BRAD
LinkDB: A0A1I7L680_9BRAD
Original site: A0A1I7L680_9BRAD 
ID   A0A1I7L680_9BRAD        Unreviewed;       698 AA.
AC   A0A1I7L680;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   08-MAY-2019, entry version 12.
DE   SubName: Full=Short chain enoyl-CoA hydratase /3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:SFV05201.1};
GN   ORFNames=SAMN05192541_111179 {ECO:0000313|EMBL:SFV05201.1};
OS   Bradyrhizobium arachidis.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=858423 {ECO:0000313|EMBL:SFV05201.1, ECO:0000313|Proteomes:UP000199591};
RN   [1] {ECO:0000313|EMBL:SFV05201.1, ECO:0000313|Proteomes:UP000199591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 26795 {ECO:0000313|EMBL:SFV05201.1,
RC   ECO:0000313|Proteomes:UP000199591};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+)
CC         + NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57318, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|SAAS:SAAS01123908};
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00324886}.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC       {ECO:0000256|RuleBase:RU003707}.
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DR   EMBL; FPBQ01000011; SFV05201.1; -; Genomic_DNA.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000199591; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000199591};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00324839};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00324863};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00331296}.
FT   DOMAIN      298    473       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      478    564       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   DOMAIN      600    686       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   698 AA;  74030 MW;  DD054A1705D806DA CRC64;
     MSEVVKLERH DEVGIVTVDS PPVNALSAAV RGGILECIKA AVADPAIKGI VLTCAGRTFI
     AGADITEFGK PPKPPALNDV LAEIENSPKP VVAAIHGTAL GGGLEVALAC HFRVAVKEAR
     LGLPEVKLGL LPGAGGTQRL PRAVGPELAV KMIVGGDPIG AAEALKNGLI EEIIEGPASG
     GEAFVRKLLA EKRPLRRLRD DDSKIAAAKA DRSIFTNAVA AMTKKSRGLE APFAAADAVG
     YAIDLPFDEG LKKEREGFLK LVASDQSKAQ RYAFFAEREA NKIAGVPEGT KSRPVNRVAI
     LGAGTMGGGI AMSFANAGVP VTLIETGEEQ LKRGLGIMQK NWEATAARGG IPADAPAKRM
     ALINGVVGIE NVGDADLVIE AVFETMAVKK EVFGKLDQFA KPGAVLASNT SYLNIDEIAK
     STKRPQDVLG MHFFSPANVM KLCEIVRADK TAPDALVTAV TIARKIAKVP AVVGVCDGFV
     GNRMLAQRGK QSEKLLFEGA LPQQVDAVVT KFGMPMGPFA MGDLAGLDIG WRSRKDRGIK
     SEIADALCEA GRFGQKTGKG YYKYEAGSRA PLPDPDVEKL IDETLLRLGR KKRVVSDEEI
     LERMMYPMIN EGAKILEEGI AARPSDIDVV WLYGYGWPIY RGGPMFWADS VGLKHIADRL
     SFYAKETNDP SLEPAPLLKK LAAEGKTFAS LAAASKAA
//
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