ID A0A1I7RPQ9_BURXY Unreviewed; 535 AA.
AC A0A1I7RPQ9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=(pine wood nematode) hypothetical protein {ECO:0000313|EMBL:CAD5215099.1};
GN ORFNames=BXYJ_LOCUS3860 {ECO:0000313|EMBL:CAD5215099.1};
OS Bursaphelenchus xylophilus (Pinewood nematode worm) (Aphelenchoides
OS xylophilus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Aphelenchoidea; Aphelenchoididae;
OC Bursaphelenchus.
OX NCBI_TaxID=6326 {ECO:0000313|Proteomes:UP000095284, ECO:0000313|WBParaSite:BXY_0270000.1};
RN [1] {ECO:0000313|WBParaSite:BXY_0270000.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:CAG9096464.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ka4C1 {ECO:0000313|EMBL:CAD5215099.1};
RA Kikuchi T.;
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CAJFDI010000002; CAD5215099.1; -; Genomic_DNA.
DR EMBL; CAJFCV020000002; CAG9096464.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I7RPQ9; -.
DR WBParaSite; BXY_0270000.1; BXY_0270000.1; BXY_0270000.
DR eggNOG; KOG3644; Eukaryota.
DR Proteomes; UP000095284; Unplaced.
DR Proteomes; UP000582659; Unassembled WGS sequence.
DR Proteomes; UP000659654; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd18987; LGIC_ECD_anion; 1.
DR CDD; cd19049; LGIC_TM_anion; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR InterPro; IPR006028; GABAA/Glycine_rcpt.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR PANTHER; PTHR18945:SF503; LIGAND-GATED ION CHANNEL; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR Pfam; PF02932; Neur_chan_memb; 1.
DR PRINTS; PR00253; GABAARECEPTR.
DR PRINTS; PR00252; NRIONCHANNEL.
DR SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000659654};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..535
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035359265"
FT TRANSMEM 442..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 510..528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 170..376
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
FT DOMAIN 384..476
FT /note="Neurotransmitter-gated ion-channel transmembrane"
FT /evidence="ECO:0000259|Pfam:PF02932"
SQ SEQUENCE 535 AA; 61842 MW; 0C7246BAB1EFACC9 CRC64;
MLLWVFLGSI IGYCDPQLSY EPLWIQSING MKSIGVHLKN FQDKYCTAEY ISRRIYYLSV
DDIDPAFGVE KATEIMRRYA YVAVRLEDVC MELQLDGVDE VGLGSNETMS EDALQLVKHS
GPIGIDVSLF NENNNRSMEK SLTEDKEIDH ILKSFDTMGK TGQKPFASTF LNPLMKKLKY
DARSPPIINE NKTVNVRVGI HVQSVSNFEL TTMDFDMDMW LRMAWRDPRL AHGLSGPILI
TEEGYLKRLW RPDAVFINSM ESFFHRVTYL NFYMFVFPEG EVFFEARVYL KPKSHLVLCK
YPHDSQTLIL QISSIAMTQD TVVFQWFPIK RDAIRVNRNI QLPELHITSY ESTVCDARRK
TGNFTCLEAR FYLKRNIGYH IAQTYVPTAT CVVFSWISVW LPEEFVEGRI FVALTVFLTL
SAESNAAKDT LPKVSYIKAI DIWFGFTASF VFSTMLQALI VIRLENMSKE KRKLVENESA
SLGVDKTVRL LIESKRLHKL SRWLDEFFKV MYPVIFLIFL FIYAFVVIQG EPTCV
//
