ID   A0A1I7SQV3_BURXY        Unreviewed;       541 AA.
AC   A0A1I7SQV3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Amiloride-sensitive sodium channel {ECO:0000313|WBParaSite:BXY_1541600.1};
OS   Bursaphelenchus xylophilus (Pinewood nematode worm) (Aphelenchoides
OS   xylophilus).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Aphelenchoidea; Aphelenchoididae;
OC   Bursaphelenchus.
OX   NCBI_TaxID=6326 {ECO:0000313|Proteomes:UP000095284, ECO:0000313|WBParaSite:BXY_1541600.1};
RN   [1] {ECO:0000313|WBParaSite:BXY_1541600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A1I7SQV3; -.
DR   WBParaSite; BXY_1541600.1; BXY_1541600.1; BXY_1541600.
DR   Proteomes; UP000095284; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.820; Acid-sensing ion channel domain; 1.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   InterPro; IPR001873; ENaC.
DR   InterPro; IPR020903; ENaC_CS.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF248; DEGENERIN-LIKE PROTEIN UNC-105; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
DR   PROSITE; PS01206; ASC; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU000679}.
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  60395 MW;  9BC902E01C46BC06 CRC64;
     MTQSATQEGA KTVLSTTTKT STAQSASTSS ITASSKEARL ETTATQTAKT VVKNTSTSPT
     SLGTSAFTTS PLVDPGTLAD LFGLSSNDNQ VTINANMLVS MQIVAAGLTQ TERDEVSYQL
     PELISTCTID GRPCNMDRDF DQRFDVDYGY CYTFNYAEPS GFYNATNFGA DHGLQIITIV
     DEDEYLESTE FQGVKVVVHP QNTWPFPNQE GYFARPGAGF GIMVRRNSFS RLGKPYGLCD
     TLDSISARKQ QFLFNGTYST EGCLRSCFQT KIAETCGCFD ARFPEVNDTE VCTPVNADKY
     KCYTDYIEKN GDYYFADCEC DSPCQNDAFG GDVVNFHWPH GPFFVDKACA NLSASEDCIE
     YYRKNTVLVQ VYFTQFGYES LEESPDQAVN FEDRKIAVDF TDLLSNLYGN TGLWIGWCII
     TVGELVLTFL QMITWICRTK YEIPEVPSCR RRNYPECEED EEENTAVTAS GEYSCNTNAV
     DMRNIMASKR KSMKNHANTD KTSSQRPVDL DKYCGIYEPT YNNILKVVYP SDIATVRPAF
     E
//