ID A0A1I7STQ5_BURXY Unreviewed; 416 AA.
AC A0A1I7STQ5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=(pine wood nematode) hypothetical protein {ECO:0000313|EMBL:CAD5221270.1};
GN ORFNames=BXYJ_LOCUS6594 {ECO:0000313|EMBL:CAD5221270.1};
OS Bursaphelenchus xylophilus (Pinewood nematode worm) (Aphelenchoides
OS xylophilus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Aphelenchoidea; Aphelenchoididae;
OC Bursaphelenchus.
OX NCBI_TaxID=6326 {ECO:0000313|Proteomes:UP000095284, ECO:0000313|WBParaSite:BXY_1642500.1};
RN [1] {ECO:0000313|WBParaSite:BXY_1642500.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:CAD5221270.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ka4C1 {ECO:0000313|EMBL:CAD5221270.1};
RA Kikuchi T.;
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CAJFDI010000003; CAD5221270.1; -; Genomic_DNA.
DR EMBL; CAJFCV020000003; CAG9108101.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I7STQ5; -.
DR WBParaSite; BXY_1642500.1; BXY_1642500.1; BXY_1642500.
DR eggNOG; KOG1453; Eukaryota.
DR Proteomes; UP000095284; Unplaced.
DR Proteomes; UP000582659; Unassembled WGS sequence.
DR Proteomes; UP000659654; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20806; C1_CHN; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR020454; DAG/PE-bd.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR46075; CHIMERIN FAMILY MEMBER; 1.
DR PANTHER; PTHR46075:SF2; RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00008; DAGPEDOMAIN.
DR SMART; SM00109; C1; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000659654};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 45..114
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 167..217
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 230..416
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 416 AA; 47611 MW; 5CD09BE4DA17AD00 CRC64;
MEEDENMNDT YWKHNLYLLQ EKAPKPKVVP CSRRIINRPA HYGIEYHGLI ERTEAEEKLR
ENGEGAFLVR ASKRSPDANT LCMLFDGNVM NYKLYYDGCH FVAEKRFDEL SLLVADGLIS
MYIDKYASEY IRKMADEAVY EQSPYSQYTK FNENQSRSVA SPVPRQPHDF ISFTFKMPHY
CDYCRNFLWG LVQQGVRCNN CGFAAHRKCS DRALDDCRPD CKYVKRMFAV DLTTLCMAHG
VSVPPVITQC INEVEKRGLN VEGIYRVSGS HDQMEKLRRQ FDLGTAVDLN AIDDIHTVAG
LLKLYLRLLP QQLVPFTVFS SLLNAFNSTR STRERTLRCR QALEALTSVN LRTLSEILGH
LRVVASYAES NKMSEENLAT IFSPTIFCTG TVPSLPQQQH VLLHFLIVTP KVTDAN
//
