ID   A0A1I7SYP2_9PELO        Unreviewed;      1116 AA.
AC   A0A1I7SYP2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=MIF4G domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold335.g832.t1};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold335.g832.t1};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold335.g832.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; A0A1I7SYP2; -.
DR   STRING; 1561998.A0A1I7SYP2; -.
DR   WBParaSite; Csp11.Scaffold335.g832.t1; Csp11.Scaffold335.g832.t1; Csp11.Scaffold335.g832.
DR   eggNOG; KOG2051; Eukaryota.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 2.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 3.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          22..223
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          411..602
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          623..845
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          368..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          808..827
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          887..935
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          993..1023
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1089..1116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          249..276
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        809..827
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        903..926
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1000..1018
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1116 AA;  128452 MW;  59CC99475C31A032 CRC64;
     MIEIRENTLD NEKELRSLDS TLKKTTSFMK KVKLLSASTV PQLIEELSKL NLSKFVEEMA
     SGIIETKLKL SDIPKVTELC LAISAKYSNF SEQIAGEFKR VLPVKKSDKI ANVAKLRVDI
     IFLAELCLCG VFNEKEGLQV LGAVLSYLIQ TDKTEFVNVG LLATVSRAVG WQIANIIPIP
     LTDDVETVEI KEGDLSVSSA LSDDQKKSIR ELFKSYYDSL YSKTEKVCSA RNKAMKKVKR
     QERVRGDAAD EEKTKLNDLQ TELDTLRKMA SEIARATGVQ MKPLKEEASD DEEDEAANLE
     MGRQIAEGEI KMWNDEETKA FYEDLIDLRL MVPKDLYKES EQRTLSKAKM AERIEDIDVE
     NINEAGAVDG KRNSIQRADS EKETSPEESN IQTVLKEVTD SSEDRGVNKW QKFVLDLDHL
     VSKYSTDKAA EYFVSNLNNK GCRKRLVKLM VDPPPTRIDV VPFYARLIAT LENVMPDLTT
     EIVTQLLEKF RGFLQQKSSA AYDIKVERKM VCVMMIAELM KFGVVSRAEG LSCLRQLVYD
     LRGHSVEMTA TFMESGGLYL YRHTESHAKM KRLLEVVKAK RERMKDQRQT MLIDNAYFTC
     LPPEDSKEER LRLKLDEEDT PMKRFIRHII LDINEDSIEV FLKCFRRLDW SDPEISDYAI
     RYLSSTWLLP INNLQHVASA IAGLCNLEHF QWIGMAVIDA TIETIRISLE NPGSFNQWAH
     SAAVYLAELY SFELCDEDLI LQVLYQIISY PEPENSWKDL HRIRMVCAVL EIVREFFEKG
     SGTVKLRYFM TYFHRYYFTK KEAWDQETAP EQQLGSSPDT SENEIIPDVQ TSFPYEVEFA
     YTEICRRFRK KKSSPYRWPR NLKEAQDAVR RIEKKFKGEL KEIAGDLSDI EDTTSSAQKD
     LNVIEEDDED EYGENRDSDM EDEDSEEERQ KGFTETNVVT KEEDDDFQRE LDRMMGEGFR
     QTAAPAVAPQ YDVTLPAAAK NRFNRNIKFA ENTKAESSFS RSIEFDDDEP KSSNAVSTDR
     HEQSRVTLMI RGKANKPSLK TVNIDDDSLQ EKWKQEKARE EQERADMKRL TLGQHRRIEL
     EEEKALLAQL NNSRKGNAKK NPPRPKFPKP HLEGEW
//