ID   A0A1I7SYX1_9PELO        Unreviewed;       844 AA.
AC   A0A1I7SYX1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Glutamate receptor 1 {ECO:0000313|WBParaSite:Csp11.Scaffold36.g156.t1};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold36.g156.t1};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold36.g156.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC       family. {ECO:0000256|ARBA:ARBA00008685}.
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DR   AlphaFoldDB; A0A1I7SYX1; -.
DR   STRING; 1561998.A0A1I7SYX1; -.
DR   WBParaSite; Csp11.Scaffold36.g156.t1; Csp11.Scaffold36.g156.t1; Csp11.Scaffold36.g156.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR001508; Iono_Glu_rcpt_met.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR18966:SF600; GLUTAMATE RECEPTOR 1-RELATED; 1.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   PRINTS; PR00177; NMDARECEPTOR.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        491..513
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        565..587
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        770..792
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          357..746
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
FT   DOMAIN          367..435
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
FT   REGION          799..844
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   844 AA;  96856 MW;  91B85177689D5C76 CRC64;
     MLRLAEMTFN ALSDVDFDVL LGTRDLPPME MATMMWNLNR ITDRTLRTMF SYLHKKSPRY
     QLFVDNYVAP NDEEMFKEFL NEFHRRISTQ HTLKSNDSSE EIDEPIPVNV IVDLEGSYRT
     RAFLRALEES VLVKKEYHYV FSNFDVDEID LSGFHFSLIN ITIFRIFDKN NKKFLKTRAE
     FHDVYRGEFS NTDNIPTAAA FAHDAILVAG RALQIAMNEH GKGIFDKSFV RHQLFNRGKK
     GLYCRPHEDQ TEVRQFEGFE HGEKISDAIK KVILTEKDGT LTGRIQFDQK TGRRTNFSAE
     IVEIKPGVNS LNSIWERFQW AQDEGFLLGG ERYVQEKKKD SSQTRKGILP SKPWKLRFNV
     VTVLVKPFVM LKRRNPGEPE LKGNDRFEGY CIDLLNLLAK NITGFEYDVF ISDGNKYGSR
     QADGSWDGMI GYLLNETADV AVAPLTITQE RERAVDFSKP FMTTGISIMI KKPEKQEFNI
     FSFMEPLGMT IWIFTLSSYF GVSLTIFLVS WFSPYEKRIE FKRGEFTVTN EFTLYNSLWF
     TLAAFMQQGT DILPRAVSGR IASSCWWFFT LIIVSSYTAN LAAFLTLERM TPPIESVDDL
     ANQNKILYGV VEGGSTAAFF EDSIVPLYKK MWNFMVSTTQ KQIELEKQSI SNSTSNRIFV
     SSYADGIEKV RTSKGKYAFL LEETTNNYES GRRPCDTMKV GQNLNTLGYG IASKIGNPLR
     VSLNLAILYL SEKGELKKLE NKWWYDRGQC DTGTSDGGTS SSLNLSKVAG IFYILLAGMV
     LSMCTALIEF LFRKNKENRE KERNRMRNSR QQKPGIVASC AKAKQHQNRR TKSEEVTTPR
     STLF
//