ID   A0A1I7SZI9_9PELO        Unreviewed;       569 AA.
AC   A0A1I7SZI9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold41.g209.t2};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold41.g209.t2}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   AlphaFoldDB; A0A1I7SZI9; -.
DR   STRING; 1561998.A0A1I7SZI9; -.
DR   WBParaSite; Csp11.Scaffold41.g209.t2; Csp11.Scaffold41.g209.t2; Csp11.Scaffold41.g209.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049163; Pif1-like_2B_dom.
DR   PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR   Pfam; PF05970; PIF1; 2.
DR   Pfam; PF21530; Pif1_2B_dom; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT   DOMAIN          498..522
FT                   /note="DNA helicase Pif1-like 2B"
FT                   /evidence="ECO:0000259|Pfam:PF21530"
FT   REGION          194..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   569 AA;  64373 MW;  CEB8F3286F8C8E6F CRC64;
     MLSRVCKGMM EAWFKSNQHP QTLPGSGRMT TRDLTLIDMF SYFKFDIKQQ KFILRKKNYS
     DRVIGRIQAP QPRYLQLLAT RLLAQNVQGP RSWEELRTVD GVVQGTCLAA RARRLMNGED
     EWDAAITEHS PAFGTGQPIR SLDETLKTNW WRTGHHGTSC RRRHTLFAIF AFCWPNRMRL
     RDYELEDHFD ADDLPEIDPR DDVDNPNVSN ESQSDHGKMA SKMYSKLNEA QKTAVDRALA
     LDAETGKERM MFVDGPGGTG KTFVYMAVYH KLKSLGKNKS KTACLTCAIA PFTDEGDTLA
     AVDAIIWDEA CMSDRRIVQA VSLLFQDLKE STLAFGGVLV MMGGEWRQIL PIVEGIQGSG
     VVEYTLKNSD LWGRIEKFHS TQNQRSIDDP AFAKMTLENG NGSNFINPLR QHVLLPEDMV
     ERGAEMKLFD WVFPNINDVP STKSAAILTM DNTTALRINE DVLDRLDGEV RTFFSNDFAI
     NKKIDSVDPA VFARETPSGM PPHRLRLKVG AQCVLLRNMS GSRIVQWDPI DVGEIWNRCD
     LFLHQPSNDN ISKGSVSSLS QDDPIWKKE
//