ID   A0A1I7T0T7_9PELO        Unreviewed;       477 AA.
AC   A0A1I7T0T7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Mitochondrial-processing peptidase subunit alpha {ECO:0000256|ARBA:ARBA00016741};
DE   AltName: Full=Alpha-MPP {ECO:0000256|ARBA:ARBA00030006};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold451.g1311.t1};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold451.g1311.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- FUNCTION: Substrate recognition and binding subunit of the essential
CC       mitochondrial processing protease (MPP), which cleaves the
CC       mitochondrial sequence off newly imported precursors proteins.
CC       {ECO:0000256|ARBA:ARBA00002123}.
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DR   AlphaFoldDB; A0A1I7T0T7; -.
DR   STRING; 1561998.A0A1I7T0T7; -.
DR   WBParaSite; Csp11.Scaffold451.g1311.t1; Csp11.Scaffold451.g1311.t1; Csp11.Scaffold451.g1311.
DR   eggNOG; KOG2067; Eukaryota.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   PANTHER; PTHR11851:SF49; MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE   4: Predicted;
FT   DOMAIN          30..175
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          185..388
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   477 AA;  53127 MW;  40D8E173583C67D7 CRC64;
     METGKVSSVN GAPVIGRNSR VTQLPNGLKV CTENTYGDFV TIGVAVESGC RFENGFPFGV
     SRVVEKLAFS SSENFMNRDD VYAQLEESSG IVDCQSTRDT MMYAASCHRS GVDSVTKVLS
     DTIWRPVIDD ESLDQAKMIV RYESEDLPQR IEAIEILLTD YIHQAAFQNN TIGYPKFGLD
     SLDKIRVSDV YGFLSRVHTP ERMVVGGVGV DHDEFVSIIS RYFDTKHTIW NTNPSVLPSK
     IPEIDKSRSQ YTGGELRLKS DLTPLTIGKP YPLLAHVVLG LEGCSYKDDD FVAFCVLQSL
     LGGGGAFSAG GPGKGMYARF YTELMNQHHW IYSAIAHNHS YSDSGVFTMT ASTYPENIND
     ALICLVQQVL QLKKGVSSEE LARARTQLRS HLMMNLEVRP VLFEDMVRQV LGHGERKQPE
     EYAAKIEKVS NSDIERVVDR LLSSKPSLVG YGEIDKLGDL RSLDQALAKR DLRYLFK
//