ID   A0A1I7T1C3_9PELO        Unreviewed;       231 AA.
AC   A0A1I7T1C3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=VPS37 C-terminal domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold460.g1468.t1};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold460.g1468.t1};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold460.g1468.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular
CC       trafficking process. Required for the sorting of endocytic
CC       ubiquitinated cargos into multivesicular bodies. May be involved in
CC       cell growth and differentiation. {ECO:0000256|ARBA:ARBA00025010}.
CC   -!- SIMILARITY: Belongs to the VPS37 family.
CC       {ECO:0000256|ARBA:ARBA00007617}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A1I7T1C3; -.
DR   STRING; 1561998.A0A1I7T1C3; -.
DR   WBParaSite; Csp11.Scaffold460.g1468.t1; Csp11.Scaffold460.g1468.t1; Csp11.Scaffold460.g1468.
DR   eggNOG; KOG3270; Eukaryota.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0000813; C:ESCRT I complex; IEA:UniProt.
DR   GO; GO:0009056; P:catabolic process; IEA:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   InterPro; IPR009851; Mod_r.
DR   PANTHER; PTHR13678:SF27; LD45836P; 1.
DR   PANTHER; PTHR13678; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37; 1.
DR   Pfam; PF07200; Mod_r; 1.
DR   PROSITE; PS51314; VPS37_C; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          96..185
FT                   /note="VPS37 C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51314"
FT   COILED          78..112
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   231 AA;  25305 MW;  B3809EA74E247706 CRC64;
     MFGQNAYESH VDLAVSAASA NLRNMSNEQL IALLDDETLL ESIIVNLPQV RSMPTDKESA
     LAANKSLAEW NLAQKPRIDA AKTQSIDLYE KVKKLQEEVT VLKSQLDSIS SSKSLDTTSS
     LMQVAAQEAD DDAEALFTQF ENGEVSIDIF LKQFKDKKAS AHLRKIKSDR LAALLREQTY
     SYANPAVAPP MQQPGYPTGN HMPGIGNIPF GSGYSGYPNI SQPSAGRHPF F
//