ID   A0A1I7T1X1_9PELO        Unreviewed;       616 AA.
AC   A0A1I7T1X1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Peptidase_M1 domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold470.g1628.t2};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold470.g1628.t2};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold470.g1628.t2}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M1 family.
CC       {ECO:0000256|ARBA:ARBA00010136}.
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DR   AlphaFoldDB; A0A1I7T1X1; -.
DR   STRING; 1561998.A0A1I7T1X1; -.
DR   WBParaSite; Csp11.Scaffold470.g1628.t2; Csp11.Scaffold470.g1628.t2; Csp11.Scaffold470.g1628.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   Gene3D; 2.60.40.1730; tricorn interacting facor f3 domain; 1.
DR   InterPro; IPR045357; Aminopeptidase_N-like_N.
DR   InterPro; IPR042097; Aminopeptidase_N-like_N_sf.
DR   InterPro; IPR001930; Peptidase_M1.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR11533:SF257; PEPTIDASE_M1 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   Pfam; PF17900; Peptidase_M1_N; 1.
DR   PRINTS; PR00756; ALADIPTASE.
DR   SUPFAM; SSF63737; Leukotriene A4 hydrolase N-terminal domain; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          4..158
FT                   /note="Aminopeptidase N-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17900"
FT   DOMAIN          196..420
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
SQ   SEQUENCE   616 AA;  70046 MW;  909970BE6B58CCAC CRC64;
     MVLHFNLSSL SDNITLDAVD LHSFRNISLI RSSDLTEPTL KSIKILKETV EFKFEKSLFP
     GQYLLTIGEY NGRIGNASEG LFERRHPLLY TTHLQPNHAR RLFPCIDHPA VKALFRLSIV
     HPTDTVAQSN TIAMDVHVEN RKWQRTIFQA TPLLPAYLVA FSVMPDTNLQ LSRQTSFGVT
     VRVNGESRGI VLRVLDCALA SFEILAGLID VPLPLNKIDF ILVPDYDGGM ENWGHITVSE
     TLATSGDDAH LIYLVCNETH RIAIISKNSV KEHIAHEIAH HWIGNRATID SWNWICLQED
     LADWMALKAV KALLTDEIRL QRFQLAQYVE IQLVEDFLSP GHSLYMPSKI TQELINRHCY
     LKGVVLLDTL ESVVGEQFMY SVIKSLVASH STFNLTTFTS YFDQIRVDRN ATVGQIYEYW
     YTTGGYPSIL VENNGPSSRL QQLSRPLWPL KMTSTLSIPQ FVFSESIVFA SESAPLLVNL
     NFTSFMRVNY DSLTWTAIFK YMFEEPELFS AVGRAQLVSD FCYFYANDSV ENGNILKEAV
     VDMVYSKPEF FELCDWNLYW CNSRSDQSLI SQIVRSLALR FTSATFESTS AFGCKNGMAA
     RNMNQFCEKI FGRKCI
//