ID A0A1I7T649_9PELO Unreviewed; 449 AA.
AC A0A1I7T649;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Thiamine transporter 2 {ECO:0000313|WBParaSite:Csp11.Scaffold519.g2775.t1};
OS Caenorhabditis tropicalis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold519.g2775.t1};
RN [1] {ECO:0000313|WBParaSite:Csp11.Scaffold519.g2775.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|PIRNR:PIRNR028739}; Multi-
CC pass membrane protein {ECO:0000256|PIRNR:PIRNR028739}.
CC -!- SIMILARITY: Belongs to the reduced folate carrier (RFC) transporter (TC
CC 2.A.48) family. {ECO:0000256|ARBA:ARBA00005773,
CC ECO:0000256|PIRNR:PIRNR028739}.
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DR AlphaFoldDB; A0A1I7T649; -.
DR STRING; 1561998.A0A1I7T649; -.
DR WBParaSite; Csp11.Scaffold519.g2775.t1; Csp11.Scaffold519.g2775.t1; Csp11.Scaffold519.g2775.
DR eggNOG; KOG3810; Eukaryota.
DR Proteomes; UP000095282; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0090482; F:vitamin transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002666; Folate_carrier.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00806; rfc; 1.
DR PANTHER; PTHR10686; FOLATE TRANSPORTER; 1.
DR PANTHER; PTHR10686:SF20; FOLATE TRANSPORTER 1; 1.
DR Pfam; PF01770; Folate_carrier; 1.
DR PIRSF; PIRSF028739; Folate_carrier; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR028739, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|PIRNR:PIRNR028739}.
FT TRANSMEM 49..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 449 AA; 50957 MW; 2F30C5D605D144FB CRC64;
MDWRTTTAVL CLYGAVKEFR PATPFLTPFL ASPEKNLTLD ELYSQVYPYW TYSYMFALIP
MFILTDILRY KPIVMIEAIG LVVTWSLLVF GNGVWQMQIM QIAFGVASAA EIAYYSYIYS
IVDRKHYKRA TSYIRAAALF GKLLAFGLGQ TLISTHTSGY LTLNQISLGA VSLVTIIAFF
LPRVKSEKAK VSMRALPSVI EDQDIELVTN EQKEQKVNYT REYLKKTLEE LKICSRNQEL
LKWSLWWALA SCGVYQIQNY TQSLWKQMQK DPDDVANGVV EFVNTALGAF LSLFVHHLSI
NWTRHGQMIL FVTSAIVSAL LYLCSQTETV MIAYVSYVII ASIYHMLITA ASVNVAKELS
SNNHGLVFGC NTFVAVCLQS FLTLIVVDSR FLHLDIKTQF VVYSGYFAIV AAIFAFFFVI
SLFFKTTRAS KTDEISNENR TNEVFPDEN
//
