ID   A0A1I7TCM7_9PELO        Unreviewed;       617 AA.
AC   A0A1I7TCM7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=PBPe domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold582.g4605.t3};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold582.g4605.t3};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold582.g4605.t3}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC       family. {ECO:0000256|ARBA:ARBA00008685}.
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DR   AlphaFoldDB; A0A1I7TCM7; -.
DR   STRING; 1561998.A0A1I7TCM7; -.
DR   WBParaSite; Csp11.Scaffold582.g4605.t3; Csp11.Scaffold582.g4605.t3; Csp11.Scaffold582.g4605.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR001508; Iono_Glu_rcpt_met.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF411; IONOTROPIC RECEPTOR 25A; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   PRINTS; PR00177; NMDARECEPTOR.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        523..548
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          179..501
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
FT   DOMAIN          189..248
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
FT   REGION          576..605
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  70517 MW;  5650DD0ECE04B8AF CRC64;
     MYVLTKDITA FKCDSCESAL MFWMRPFPVG KIMEIRDLDD YLFRNEIGLE LDYSINGWDS
     LNVAFYMNVM GYAFETIREM NATFDVLPTF TCEAGPSEPN ITTTVREVVL NDPAHEYGNY
     TESSPNLFFQ NLEVRIYKID RDRDHEDALF NKEVGVWTPT SKLSVMYGTL QVDVRNLNIF
     RVVTLIQPPF VQRTGDPNTP YEGYCIDLIN MIQVEVNFTY TIYEVEDGSF GTMDDNGNWN
     GLIGALVSGS ADIALAPLSV MAERENDVDF TVPYYDLVGT TILMKKADVE YSLFKFMKVL
     EWPVWLCIVA AYLFTSILLW IFDRFSPYSF TNNKESSLDD LAKQYKIEYA PIKGSASETY
     FRRMAEIEET FYNMWKEMSL NESMSPRDRA KLAVWDYPVS DKFTNMWRYM QESKLPPDMD
     AAVDRVLNSV DGFAFIGDAT EIKYAALTNC KLQQVGTEFS RKPYAIAVQS GHILKDKISS
     AILMLLNQRR LETLKEKWWT DNPNKVNCPD SSDESDGISI QNIGGVFIVI LAGIALSIVT
     LAFEYYYYKR KARKAAEKEK EQIEMKIQQV IPNGVHQNGI KQDGPKTVNG TNGNGNAVQR
     TKRSNSVSAY ENTAFQY
//