ID A0A1I7TDT6_9PELO Unreviewed; 710 AA.
AC A0A1I7TDT6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DNA_MISMATCH_REPAIR_2 domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold589.g4948.t1};
OS Caenorhabditis tropicalis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold589.g4948.t1};
RN [1] {ECO:0000313|WBParaSite:Csp11.Scaffold589.g4948.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR AlphaFoldDB; A0A1I7TDT6; -.
DR STRING; 1561998.A0A1I7TDT6; -.
DR WBParaSite; Csp11.Scaffold589.g4948.t1; Csp11.Scaffold589.g4948.t1; Csp11.Scaffold589.g4948.
DR Proteomes; UP000095282; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03281; ABC_MSH5_euk; 1.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 454..470
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 689..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 78904 MW; F61311C1076A9F1A CRC64;
MRSFGALLLF LDETRLGVEM EPLTVTPPIK SIKTFTLFVS FNCVTHSMMS FSEHLVDIDY
NTIQALDILP KEVESKKSAG KNQSLFSLVD RCRSTVGKKC LRKWFRNPTT DRAVLVSRQI
CVHYFKQDWN AEVTAKVAST LGKVKALNIS NELNAETSLL REVSEVACIA GSIINFAESK
IQGRVTVMPG IDDELDKLRD TYESMPMMLT AIAKQESLRL GLTPFHNVAC VYIPLVGFVL
SLPTDFPAES HEDMSLVYAT SDELRVKNVT TERLDEEYGD ILMKLIDSQT AIILTLKLTV
MKKRRSITKL LNLAARIDAL VALGLIAAEN GWNCPTLVDE PIIEALELYH PISVLVVKKN
FVPNEVSSGR NGIKASIITG PNACGKSVYM KSIGILAFLT HIGSFVPARH AKVGLVDRIV
TRMFTVDSVL DGMSTFAKDV EQVALALRKA TGSSLVIIDE FGKGTMTEVG LSLLASCMTY
WMQKGPTHCP HIFLSSHFHS LPKFIPLDLN IATFLTFTVL REPGGQIKYL FRLTPGTVDC
SFAMAVAKEE GIPMPIIARA CRIYKAIKAG TPLKEVRAEV KTTDDEDQMV FDMDIVLADD
NGFMDAIETF VTRDKEKAFE ELNKSSMSEK TKDVEEREED VISTSKWHIE RNRRARTASI
VSSRSIASMD QISVLDFLLP KKKMKVVSTE ESEVTSEFSR SPDPFSDDGV
//
