ID   A0A1I7TRF2_9PELO        Unreviewed;       454 AA.
AC   A0A1I7TRF2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Cell death abnormality protein 8 {ECO:0000256|RuleBase:RU910716};
GN   Name=ced-8 {ECO:0000256|RuleBase:RU910716};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold629.g11022.t2};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold629.g11022.t2}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU910716}.
CC   -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC       ECO:0000256|RuleBase:RU910716}.
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DR   AlphaFoldDB; A0A1I7TRF2; -.
DR   WBParaSite; Csp11.Scaffold629.g11022.t2; Csp11.Scaffold629.g11022.t2; Csp11.Scaffold629.g11022.
DR   eggNOG; KOG4790; Eukaryota.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018629; XK-rel.
DR   PANTHER; PTHR16024:SF6; CELL DEATH ABNORMALITY PROTEIN 8; 1.
DR   PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR   Pfam; PF09815; XK-related; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW   Transmembrane {ECO:0000256|RuleBase:RU910716};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT   TRANSMEM        43..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        76..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        127..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        218..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        278..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        318..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        347..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        377..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
SQ   SEQUENCE   454 AA;  53130 MW;  FAD2E7D7509F36FF CRC64;
     MRLKKHESKF LLIPKSQDHE DAGIIPVCTD RIPSVLIVRW FDLFCFGFAM CSYVLDFFSD
     IGIAIFHFLA GRHLSGALVL TFALLPSIII NIISMVWMLD DEMHWKRRAH PRRIGTFELN
     GKRFISLGKM IALCLFQMGP LFWYYKAFYY GWMFFKSEKD NTDGEKKMFF IKMVEAERDA
     TFLRFFEAYL ESAPQLIIQG SIAANYFQNY YLSGSYPYWL YFQAASLTLS IISISWSVVV
     QNRSLRMVSE NKVNIWPHEA VLQFCWRFLT ISSRIITLVA YVLVFGIYMI PLICAHLIVT
     FAHVIFLQAL HYESHTHMEI LLLFINTIIH IFTPFNMADG QTRYRHLAAY TVEFLEMITI
     FIWLPSPLDT FPFIDKVRYG VPIAFTIGIF IMMIYYQFFH PNRRQHVNDT ETNESPLISI
     KTFEKVDNVE DSSEKTVKID DEPVSECDFV KTST
//