ID A0A1I7TWZ7_9PELO Unreviewed; 528 AA.
AC A0A1I7TWZ7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059};
DE EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};
OS Caenorhabditis tropicalis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold629.g12634.t1};
RN [1] {ECO:0000313|WBParaSite:Csp11.Scaffold629.g12634.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00000301,
CC ECO:0000256|RuleBase:RU362059};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167,
CC ECO:0000256|RuleBase:RU362059}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167, ECO:0000256|RuleBase:RU362059}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|RuleBase:RU003718}.
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DR AlphaFoldDB; A0A1I7TWZ7; -.
DR STRING; 1561998.A0A1I7TWZ7; -.
DR WBParaSite; Csp11.Scaffold629.g12634.t1; Csp11.Scaffold629.g12634.t1; Csp11.Scaffold629.g12634.
DR eggNOG; KOG1192; Eukaryota.
DR Proteomes; UP000095282; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF89; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU003718}; Membrane {ECO:0000256|RuleBase:RU362059};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU362059};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003718};
KW Transmembrane {ECO:0000256|RuleBase:RU362059};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362059}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|RuleBase:RU362059"
FT CHAIN 18..528
FT /note="UDP-glucuronosyltransferase"
FT /evidence="ECO:0000256|RuleBase:RU362059"
FT /id="PRO_5009029857"
FT TRANSMEM 494..517
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362059"
SQ SEQUENCE 528 AA; 60361 MW; F62F5D80B7962367 CRC64;
MIIQSFLLLF SVLSLNAFNI LVYSPSFGGS HTNFMARLAD TLTEVGHNVT FLIPVADEAR
KGQLGVKKTK DVVIVEQDDE MRSQIKPIDD DMAQYWTTEM DSSNSDTIFQ VFIDAMQLSC
ENFMRNKEVF EEMKSREFDV GIFEPVSVCG LGFMNAIGIE KIIMASSCAL YDGAVAAVGE
PLDFSYVPGM MSKSGEKMSL TERLENYRMS MTSYRMQYGM WDKETEIYRK QLGENIPHWR
DLMPTSSVFF TNSIPYIDFP RTVTQKTVPI GGISVDIQSI RSQKIPIEWS TVLDERPFNM
LISFGSMVRS MDMPSEWRRG LLETIKSEPN VTFIWKYEND DISWANGVRN IHFSKWVPQT
ALLNDDRLTA FMTHGGLGST NELAHLGKPA LMLPVFADQD RNANMLARHG GVKVIHKSEL
ANTKKIKNAI RSILHDEKYK KNAEKLAELL TNQPMKPKEQ VIKYTEFVAR FGPFPQMDSY
GRRLGFIERN LLDVYSVIGF SYLFTFSLIY FGIRFILNRI PLKLIKKE
//
