ID   A0A1I7TXD7_9PELO        Unreviewed;      1397 AA.
AC   A0A1I7TXD7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=LSDAT_euk domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold629.g12748.t2};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold629.g12748.t2};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold629.g12748.t2}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   STRING; 1561998.A0A1I7TXD7; -.
DR   WBParaSite; Csp11.Scaffold629.g12748.t2; Csp11.Scaffold629.g12748.t2; Csp11.Scaffold629.g12748.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR041491; TRPM_SLOG.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   PANTHER; PTHR13800:SF44; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF18139; LSDAT_euk; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        949..968
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1011..1030
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1042..1059
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1079..1098
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1177..1198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1218..1240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          133..396
FT                   /note="TRPM SLOG"
FT                   /evidence="ECO:0000259|Pfam:PF18139"
FT   DOMAIN          952..1205
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          840..885
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1357..1397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        862..885
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1397 AA;  158364 MW;  BFE5C6A6E2122F66 CRC64;
     MTNSENDEQP GPSRISPDQS NGDKTLNVVP VINVLLCCTQ LTMGGSKTAL EKIKWMKETF
     SRLECSRFVS SIFDSKKCSC GRHQEAHRDI PEFPLEFPGQ RIEEWNFEKD SVQFPTNAFG
     RLEFHCAPHP FRAQYIRLSA DTEPALIMSL LEDVWQISPP RLIITVHGGT DDFELQPKLV
     RAFCKGIWKA VSTTGAWIIT SGCNTGVAKL VADALNGAQS AVRNKIICIG IASWGMLKKR
     QDLIGEGRTV TYYSSPSNGS GTLNNRHSHF LLVDDGTVGR NGADLILRKR LEMFISQKQK
     TVGGSRNVPV VSIVLEGGLR MIHTVHDYMT DIQSIPVVVC DGSGRAADLL AFAHQNITQN
     GFLSDGICSK LFELIKKTFA CSGARAHQVL RELTACAQNK NLLTVFRLGE NREQDVDHAI
     LTALFKGKNC SPPDQLALAL VWNRVDIARS DIFALEYEWH PTILHKAMMK ALLHDRVDFV
     HVLLEQGVDM TKFLTISKLE KLYNTNKGPQ NTLYYIMADI VRVKPGHCFR LPDIGVAIEK
     LMGNGYKSFY SSSEFGERYE RWKNMKEAKK KTTDSVVPTA VNNRDPDLGT VNQAALSGTK
     QLSNHMIRRK AFHKNPTHSS RSLNLNESHD CASELEEERL FAFDGMHVEP DFRYPYNELM
     IWAVLTRRKD MAMCMWQHGQ EAMAKSLVAC RLYENLATET AEDHLAVGYY DELKECAEKF
     RTLSVELLDY CYHADDTQTL HLLTHELSNW SNRTCLSLAV MVNNEPFLAH RCCQILLADV
     WHGGLRIRTH SNLKVIAGLL FFPSILLLEL KEREELSNEP VTAPEEQNLM NLCSSHISTR
     RSNSTAIDTS SSEEDEEDDS LQLNTNGSPT AESEKTGSSP LSPRNWFSCH GTNKNRANMS
     NRFSACAPVS TPSKNGNSTN RPSRMKTAFK EIKASKRFYE FYSAPITTFW SWTLSYALFI
     FLSTYTLLVK TPQNPTMLEY FLIAYVGVYT MEQFRRILIS DVQSCLQKVR LYLSSFWNCI
     TILACFVYIV GFFYRTFGDP KVGRVILACA SVFWTVKILD YLSVHPKIGP YVTMTGKMIQ
     NMSCLVIMLA VALFSYGLPR QSITYPDEEW HWILVRNIFL KPYFMLYGEV YADEIDTCGD
     EAWENHLENG GPVILGNGTT GTGCVTGFWI PPILQPAFML VANILIISML NALFNNVYNT
     TIEKSQQIYL FQRYRQVMEY AATPFIPPPF TILQYIYYLV KFIRVAIKNR GKSKEERKSI
     RSMFDSSLKL FLDYDQIEKL HYFEEDCMDD LLRKKQNEEN SSNKRNEIQE HIRMLLDQNS
     APEFGQFKSP SAEHITMEIQ PSIIKLHGSE LSLRRNGSEE YTSITDSIDV GNSERGNQIH
     RSNSNSNDGS GANSDVE
//