ID A0A1I7TY65_9PELO Unreviewed; 369 AA.
AC A0A1I7TY65;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Nuclear receptor domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold629.g12973.t1};
OS Caenorhabditis tropicalis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold629.g12973.t1};
RN [1] {ECO:0000313|WBParaSite:Csp11.Scaffold629.g12973.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993, ECO:0000256|RuleBase:RU004334}.
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DR AlphaFoldDB; A0A1I7TY65; -.
DR STRING; 1561998.A0A1I7TY65; -.
DR WBParaSite; Csp11.Scaffold629.g12973.t1; Csp11.Scaffold629.g12973.t1; Csp11.Scaffold629.g12973.
DR eggNOG; ENOG502TGA0; Eukaryota.
DR Proteomes; UP000095282; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06157; NR_LBD; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR45886:SF16; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR PANTHER; PTHR45886; NUCLEAR HORMONE RECEPTOR FAMILY-RELATED-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 29..109
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 147..369
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 369 AA; 42276 MW; 2EAC525CB55EFE90 CRC64;
MSTPDSVNSD YLPADLEVAL IDSTSNAPME KCAVCGKPAF CYNYGVLTCN ACKMFFRRVE
VDQITYTCKQ RNSCYDGHEF IVKGSTPRCR SCRYQRCLQL GMKYIAPEKS RLALINRLDK
EFVSIIESLM FFDSRRAHRI YHCYTEEDPT LHEMVTKKSS QLVVKTKNQK VGIHEWSFLA
IYTTVELFLS FDFMQKMSVE DKVVLLQNFA MKSMVFNGAM RALANNTERV MSPDGSEVYP
DILYELKIFS VEFLNGIRSR LVARLRELKV TKEEHVLLNA VLFCNPAIQP LSSATKKLIT
CRQKSYSAAL FQYCLLTYQQ SGPSRFADLL SICTVLNRQA VDVSSLSTLF QIRLPSIQYK
KLFVDVCQK
//
