ID   A0A1I7U4S9_9PELO        Unreviewed;       480 AA.
AC   A0A1I7U4S9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Nuclear receptor domain-containing protein {ECO:0000313|WBParaSite:Csp11.Scaffold629.g14848.t1};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold629.g14848.t1};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold629.g14848.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC       {ECO:0000256|ARBA:ARBA00005993, ECO:0000256|RuleBase:RU004334}.
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DR   AlphaFoldDB; A0A1I7U4S9; -.
DR   STRING; 1561998.A0A1I7U4S9; -.
DR   WBParaSite; Csp11.Scaffold629.g14848.t1; Csp11.Scaffold629.g14848.t1; Csp11.Scaffold629.g14848.
DR   eggNOG; KOG4215; Eukaryota.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd06960; NR_DBD_HNF4A; 1.
DR   Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR049636; HNF4-like_DBD.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   InterPro; IPR001628; Znf_hrmn_rcpt.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR24083; NUCLEAR HORMONE RECEPTOR; 1.
DR   PANTHER; PTHR24083:SF183; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-49; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   PRINTS; PR00398; STRDHORMONER.
DR   PRINTS; PR00047; STROIDFINGER.
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
DR   PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004334};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU004334};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU004334};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT   DOMAIN          8..83
FT                   /note="Nuclear receptor"
FT                   /evidence="ECO:0000259|PROSITE:PS51030"
FT   DOMAIN          132..393
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   REGION          85..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..131
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   480 AA;  52783 MW;  15C9FB27A06FAB08 CRC64;
     MDLVDPLAEP CAVCGDKSTG THYGVISCNG CKGFFRRTVL RDQKFTCRFN KRCVIDKNFR
     CACRYCRFQK CVQVGMKREA IQFERDPLGG SPNSGANING TPFKKERSPG YENGNGASQG
     GGASQETPRS ANQPGVIDAL MEMEARVNQE MCNRYRRSQI FANGNGEPMA DSGIQAGESS
     AFAPPTNRPC TTEDLNEISR TTLLLMVEWA KTIPPFMDLT MEDKIILLKN YAPQHLILMP
     AFRSPDTTRV CLFNNTYMTR DNNTDLNGFA AFKTSNITPR VLDEIVWPMR QLQMREQEFV
     CLKALAFLHP EAKGLTNASQ VMIRDARNRV LKALYAFILE QMPEEAPTRY GNILLLAPAL
     KALTQLLIEN MTLTKFFGLA EVDSLLSEFI LDDINDHTSA PVSLQQHLQS PVALPANGVS
     PLNGGVGSSV ASVVSSILPT GILSSTLAAP LAIHPLQSDS ILNGNLLLNS VVNEQKPTIE
//