ID   A0A1I7V057_9PELO        Unreviewed;       370 AA.
AC   A0A1I7V057;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold630.g21080.t2};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold630.g21080.t2}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   AlphaFoldDB; A0A1I7V057; -.
DR   STRING; 1561998.A0A1I7V057; -.
DR   WBParaSite; Csp11.Scaffold630.g21080.t2; Csp11.Scaffold630.g21080.t2; Csp11.Scaffold630.g21080.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          29..362
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   370 AA;  41210 MW;  7E933AEE96EA904E CRC64;
     MMLLALSDPT LSVSCPEVTT EMHERLNFPK VELHLHLDGA ARFDTLLELS QEKGISLAGA
     KTVDELKKVL VTHEPANLSK VLEAFEIFLP VIRGDLTAIE RVAYELCEDQ HHNGVVYFEG
     RYSPHLLLCN DYPEVTAAHV VAAVKKGFDR GEKQFGIKAR SILCCIRGLD KKFPQLILDL
     ATDLKQLGVV AIDVAGSAHG ADEQYEPEVV AAFKEAFKRG IHRTVHAGES GGPKEVQKAI
     EDMHAERIGH GYRVMKDEQM YIDNFVNSKS VHLEACPYSS VMTGAVPLDW KNHPISRWAK
     DDVNFSISRD DPTCFDNSML SELTLAHKQV GLDVHQLWKA QLNAAHSCFL PEDEKAELVK
     LIESGEPPRQ
//