ID   A0A1I7V064_9PELO        Unreviewed;       430 AA.
AC   A0A1I7V064;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Nuclear receptor {ECO:0000313|WBParaSite:Csp11.Scaffold630.g21085.t2};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold630.g21085.t2};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold630.g21085.t2}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC       {ECO:0000256|ARBA:ARBA00005993, ECO:0000256|RuleBase:RU004334}.
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DR   AlphaFoldDB; A0A1I7V064; -.
DR   STRING; 1561998.A0A1I7V064; -.
DR   WBParaSite; Csp11.Scaffold630.g21085.t2; Csp11.Scaffold630.g21085.t2; Csp11.Scaffold630.g21085.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd06960; NR_DBD_HNF4A; 1.
DR   CDD; cd06157; NR_LBD; 1.
DR   Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR049636; HNF4-like_DBD.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   InterPro; IPR001628; Znf_hrmn_rcpt.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR46587; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR   PANTHER; PTHR46587:SF6; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   PRINTS; PR00398; STRDHORMONER.
DR   PRINTS; PR00047; STROIDFINGER.
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
DR   PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004334};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU004334};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU004334};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT   DOMAIN          36..114
FT                   /note="Nuclear receptor"
FT                   /evidence="ECO:0000259|PROSITE:PS51030"
FT   DOMAIN          164..426
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   430 AA;  49215 MW;  739376E4E8DC9052 CRC64;
     MTFCDPMDPP IPEYTHLDHE QEEAGPSTTK TEEDDGPCCL VCGRVANTGH HYGVTACLGC
     KTFFRRVVLQ KNSPKCKYKN QCRLEKSVNA KRLCRSCRYK KCLEVGMTED ALHPCRDVIG
     RRVRHHSVDS SPISTPPSIS PQLSISKMIS LCDGDHELLQ TITEMDTDIR TRTARKLGVT
     DSEEEQIHFY SPTPDYTNVS VNHGIGPSLK VDIIYLKEWV NRIPGYPDLS ARYQEHLMRR
     FCLRYTVIEH GLYTAQMPYH KNVWFLSDRT CLVSEFENLP EEIRRHLTPK VIREQKLLAP
     FTEMLIHDVA DPLRKLKPDS IEIATVKTLM LLKPTCLKEV EGEYLATESD LKTVNEVRNR
     VIAGLYTHYI KSGMDQEQVP IRISEVLHLT GGVEVCAARA LEEMHLLRVF NLSSFDQNSA
     EVIFGLYRDY
//