ID   A0A1I7V380_9PELO        Unreviewed;       422 AA.
AC   A0A1I7V380;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Amiloride-sensitive sodium channel {ECO:0000313|WBParaSite:Csp11.Scaffold630.g21939.t1};
OS   Caenorhabditis tropicalis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1561998 {ECO:0000313|Proteomes:UP000095282, ECO:0000313|WBParaSite:Csp11.Scaffold630.g21939.t1};
RN   [1] {ECO:0000313|WBParaSite:Csp11.Scaffold630.g21939.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A1I7V380; -.
DR   STRING; 1561998.A0A1I7V380; -.
DR   WBParaSite; Csp11.Scaffold630.g21939.t1; Csp11.Scaffold630.g21939.t1; Csp11.Scaffold630.g21939.
DR   Proteomes; UP000095282; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   Pfam; PF00858; ASC; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU000679}.
FT   REGION          376..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   422 AA;  49664 MW;  2E3BE26E8D62CF9D CRC64;
     MIKSYSAQPS FMRINETKNH RFSSDIELCS KEKIVCDEIL KEKETMTCKE VDAHCVLIRF
     STKTKIRLKK KGLHFKYGTE EDVHYLSSKP HTHHKIRLKV FQIERLNLER AKCITNWNEI
     LWISEDSKPD YRYSLKLCEQ IRYELTGKVE YLQYDFPCQP ACHEIQYKIS NSKLYHNSES
     VAISFSVLPV ITHMQETRKT TLVDILCYLG GASSLFMGCS CVTLMEMFVF LFKLVANSVW
     SKEAPEPDDS YYEEKYRFEF SDHRNKRRYA ICDRETMEKY LLSTNSMEVK SINLDKRLSV
     FSHSAIRKAP KLKALKDNRN FEHIDIFDEV MESDSMKEEI RTIPKDEYSV EYQDERMDTL
     GEIPNEQKRS IRPPLRRCST ATSYASHTSK GSSSLTARSF VPIQHNRRMS RAFTRNMPMN
     DF
//