ID A0A1I7V8T2_LOALO Unreviewed; 443 AA.
AC A0A1I7V8T2; A0A1S0TR17;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=ZP domain-containing protein {ECO:0000313|WBParaSite:EN70_11068};
GN ORFNames=LOAG_09931 {ECO:0000313|EMBL:EFO18563.1,
GN ECO:0000313|WBParaSite:EN70_11068};
OS Loa loa (Eye worm) (Filaria loa).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_11068};
RN [1] {ECO:0000313|EMBL:EFO18563.1, ECO:0000313|Proteomes:UP000095285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Loa loa.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:EN70_11068}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR EMBL; JH712469; EFO18563.1; -; Genomic_DNA.
DR RefSeq; XP_003145506.1; XM_003145458.1.
DR AlphaFoldDB; A0A1I7V8T2; -.
DR STRING; 7209.A0A1I7V8T2; -.
DR EnsemblMetazoa; EFO18563.1; EFO18563.1; LOAG_09931.
DR GeneID; 9947373; -.
DR KEGG; loa:LOAG_09931; -.
DR WBParaSite; EN70_11068; EN70_11068; EN70_11068.
DR CTD; 9947373; -.
DR eggNOG; ENOG502S06H; Eukaryota.
DR InParanoid; A0A1I7V8T2; -.
DR OMA; TIRFNDI; -.
DR OrthoDB; 5304671at2759; -.
DR Proteomes; UP000095285; Unassembled WGS sequence.
DR GO; GO:0032590; C:dendrite membrane; IEA:EnsemblMetazoa.
DR GO; GO:0043621; F:protein self-association; IEA:EnsemblMetazoa.
DR GO; GO:0003391; P:amphid sensory organ dendrite retrograde extension; IEA:EnsemblMetazoa.
DR GO; GO:1990138; P:neuron projection extension; IEA:EnsemblMetazoa.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR47327; FI18240P1-RELATED; 1.
DR PANTHER; PTHR47327:SF20; PROTEIN DYF-7; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR SMART; SM00241; ZP; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095285};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..443
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010213453"
FT TRANSMEM 351..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..286
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 443 AA; 49961 MW; B8560905840A2499 CRC64;
MLALRTLLTI SMLAIAINAE GFVEEVSCTA DAINVVLNKT DPDIQRWISD PKAQPVVYVY
EHKTRPPCGT AMKKGNLINY NFTIPYGVHC DVHLTDLEPN YRNAETTIAL EDNTDITPSK
AIRVNHVFCL YTRSVQTIRF NDISSGHEVV ASTGGKPKPK VEMIFRSIDG RPLRAAKFGD
IVEFYVALSP DKAYRGISPK ECMFSDREDM SSPDAKHLTF VQSSCPVDEM SEIIDPLANV
NEEVYFSKFK TFRFGNQSTV FAHCTVQVCL TTEECVQKCF KRISNLNLTA ERLRFRHRRQ
LDDDYDLTTV IRKQNAINEI ALTRPLTILD DLESNEVNDK KVEQCHINNS AIISLPIIIL
ILSLSMLSII CLTGLIFTLR RLAAYKKLTP FGIYSAYSGP TVSLPIRTLT NSTARSLTTN
GNRTTWIDQL SAGIEYPYVR EMY
//
