ID A0A1I7VAW7_LOALO Unreviewed; 284 AA.
AC A0A1I7VAW7; A0A1S0UGW2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=T-box domain-containing protein {ECO:0000313|WBParaSite:EN70_11794};
GN ORFNames=LOAG_18576 {ECO:0000313|EMBL:EJD74054.1,
GN ECO:0000313|WBParaSite:EN70_11794};
OS Loa loa (Eye worm) (Filaria loa).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_11794};
RN [1] {ECO:0000313|EMBL:EJD74054.1, ECO:0000313|Proteomes:UP000095285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Loa loa.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:EN70_11794}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR EMBL; JH712440; EJD74054.1; -; Genomic_DNA.
DR STRING; 7209.A0A1I7VAW7; -.
DR EnsemblMetazoa; EJD74054.1; EJD74054.1; LOAG_18576.
DR WBParaSite; EN70_11794; EN70_11794; EN70_11794.
DR eggNOG; KOG3585; Eukaryota.
DR OMA; QSEEHAC; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000095285; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR046360; T-box_DNA-bd.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00201};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00201};
KW Reference proteome {ECO:0000313|Proteomes:UP000095285}.
FT DOMAIN 1..17
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..168
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 284 AA; 29753 MW; 794B7665FFC2DB3E CRC64;
VTQLKIDNNP FAKGFRDAGA GKREKKRLMN RTECSTNAIG ITKSVISLND DPVTTSESPA
VRACSSMDSD RSDDDDSPPL PKRARSSQST TDDSLQTMNH HLSQNHNLQQ HLQFLQNHHR
LLSKEAANFQ FFHPSGIGSG GGGGGGGGGG GGGGGPPPPP PPPPPHFTPF FQNYGFHPAA
EFFFPATPFP REFLMHQAAA AAAAVQFSPY LLRPSLPAPS LCTSHTINPP IVSPASVTVS
QSLPSIATTV IPSTTNGTPS STPITGKSAV APKKGGFDVS DLLA
//
