ID   A0A1I7VCL3_LOALO        Unreviewed;       568 AA.
AC   A0A1I7VCL3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Thioredoxin-like_fold domain-containing protein {ECO:0000313|WBParaSite:EN70_12309};
GN   Name=LOAG_18844 {ECO:0000313|WBParaSite:EN70_12309};
OS   Loa loa (Eye worm) (Filaria loa).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX   NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_12309};
RN   [1] {ECO:0000313|Proteomes:UP000095285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Loa loa.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:EN70_12309}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I7VCL3; -.
DR   STRING; 7209.A0A1I7VCL3; -.
DR   WBParaSite; EN70_12309; EN70_12309; EN70_12309.
DR   eggNOG; KOG2501; Eukaryota.
DR   InParanoid; A0A1I7VCL3; -.
DR   Proteomes; UP000095285; Unassembled WGS sequence.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR46472; NUCLEOREDOXIN; 1.
DR   PANTHER; PTHR46472:SF1; NUCLEOREDOXIN; 1.
DR   Pfam; PF13905; Thioredoxin_8; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000095285}.
FT   DOMAIN          231..317
FT                   /note="Thioredoxin-like fold"
FT                   /evidence="ECO:0000259|Pfam:PF13905"
FT   REGION          390..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        401..420
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   568 AA;  63750 MW;  F89E5E749E49C671 CRC64;
     MSFEDLYDYC FRNIGLIHLI PSSSAKGNNE DQNELTTLDT VFTSSRYVIF YLINSTSTRS
     LEPVLSLKKL VQQRNSIFAN CPRESPARLR RFFGVSKKSK KKRLVEVDDV NVVIFDLDLN
     DNDERPHTAI SETGWYIIVP INIMAKSRLL RALHYYSTPS LIVVDASSRQ IITDDGRRLL
     QDDPDGLNFP WFNMTAEELF QGAVLRNCKD ADGTKKIVTE NFQNLKSTVK GLYFGANWCP
     PCRSFSQQLI SCYISLKNAG IPFEIFFCSS DRSQESFEHH FSTMPWLAFP YDPQKTTQLT
     RLYSVNGIPA FLLLNEENHL ITRHGRNVLL SDPTGSLFPW GSLPLYELNE NTLCRLRDEP
     SLVLFTEGSP DDVTFSMEVL RATAESLFRE RQESMKHSSS SSSKEIDNTD NNATANNDLN
     NLTYSTNSVN SSISSDISLP SWIDPLQIFY TGDDPLCDFI LEGLGLGNAE LPLIVILDAT
     ISRMCICEKP DVSSEIIAKF VADYKNGKLN MVPLPTTCQN NAQPTRYGSI PAQAVHQALG
     IGNGQSTNSI LNENQSTISS DQQIPIVL
//