ID A0A1I7VE08_LOALO Unreviewed; 725 AA.
AC A0A1I7VE08; A0A1S0UE23;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Tr-type G domain-containing protein {ECO:0000313|WBParaSite:EN70_1500};
GN ORFNames=LOAG_00130 {ECO:0000313|EMBL:EFO28353.1,
GN ECO:0000313|WBParaSite:EN70_1500};
OS Loa loa (Eye worm) (Filaria loa).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_1500};
RN [1] {ECO:0000313|EMBL:EFO28353.1, ECO:0000313|Proteomes:UP000095285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Loa loa.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:EN70_1500}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR EMBL; JH712095; EFO28353.1; -; Genomic_DNA.
DR RefSeq; XP_003135718.1; XM_003135670.1.
DR AlphaFoldDB; A0A1I7VE08; -.
DR STRING; 7209.A0A1I7VE08; -.
DR EnsemblMetazoa; EFO28353.1; EFO28353.1; LOAG_00130.
DR GeneID; 9937498; -.
DR KEGG; loa:LOAG_00130; -.
DR WBParaSite; EN70_1500; EN70_1500; EN70_1500.
DR CTD; 9937498; -.
DR eggNOG; KOG0461; Eukaryota.
DR InParanoid; A0A1I7VE08; -.
DR OMA; ENWFPWE; -.
DR OrthoDB; 54465at2759; -.
DR Proteomes; UP000095285; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR049394; eEFSec_C.
DR InterPro; IPR049393; eEFSec_III.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF11; SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR; 1.
DR Pfam; PF21131; eEFSec_4th; 1.
DR Pfam; PF21208; euk_SelB_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000095285}.
FT DOMAIN 1..139
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 725 AA; 82587 MW; 70A7D9D70B06B631 CRC64;
MGSTAAFDKH AKTSNLRANT IDLGYSTLTI DGTVIALIDC PGHASLIRSV LAASSVFDMA
IVVIDSSKGI EQQTAEHLLL VSLFCPDHVI LVINKIDLVD KKTVEQMTRR CRKVASSLKI
NSNLQVVPIS LMEYKEEGVM ALMNALHLAL YAPQRVSSGH FMMFIDHCFS IKGKGTVMTG
TVVDGICKVG MDVEIAALQE KRKIKSMQRW KEDVCSAGVG DRAALLFHNV SGKDINRTII
YEPGTLHRVQ FLLVSVNRVV HFQGILRQGS KLHVSTGFDT VIGQCQFLAS ALPEEQDHYE
VVQELDETVK FAILSLEQFV YTKEGSFFIT SRLDYQGKGC RFVFYGTFLK LLNNERQICR
FRRKKKVGKV ERIENERSII CNSLFKKETN VDTYCKMNVY LSTGEVGRLE SAFGKSGKVR
ISFLEDLPES TMTAYKNGLE IQVVLYFKKF LNDGKIKIDR MLKISLRFTL IRRVATLSFY
KSSHSLSSTS NGRSHKLVNI NIRAEATNKG KPYVKIISGT AGNPTNNEDA NFSKKGYIEI
WRKPRRREQT HTTKTLWDMR EDIDKLAKTL HRLKTNEKGQ PQKSPEVAVS KQKYEEEELR
LSTYVDSSVE RLSFVVRTPD RRVLIKKFTG ITISRTILEM LRDRKVRINE VVTYDFAIVC
KPMDTLDIWK GEFEENPAFA RVDRFQILHI LCSSCYQHFT VHAIALRDIL IENWFPWEIP
KVENH
//
