ID   A0A1I7VP05_LOALO        Unreviewed;       320 AA.
AC   A0A1I7VP05; A0A1S0TZ21;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=DREV methyltransferase {ECO:0000313|EMBL:EFO22517.2, ECO:0000313|WBParaSite:EN70_4687};
GN   ORFNames=LOAG_05975 {ECO:0000313|EMBL:EFO22517.2,
GN   ECO:0000313|WBParaSite:EN70_4687};
OS   Loa loa (Eye worm) (Filaria loa).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX   NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_4687};
RN   [1] {ECO:0000313|EMBL:EFO22517.2, ECO:0000313|Proteomes:UP000095285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Loa loa.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:EN70_4687}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   EMBL; JH712263; EFO22517.2; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I7VP05; -.
DR   STRING; 7209.A0A1I7VP05; -.
DR   EnsemblMetazoa; EFO22517.2; EFO22517.2; LOAG_05975.
DR   WBParaSite; EN70_4687; EN70_4687; EN70_4687.
DR   eggNOG; KOG3987; Eukaryota.
DR   InParanoid; A0A1I7VP05; -.
DR   OMA; FDVIACN; -.
DR   OrthoDB; 8628at2759; -.
DR   Proteomes; UP000095285; Unassembled WGS sequence.
DR   GO; GO:0106370; F:protein-L-histidine N-pros-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR007884; METL9.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12890; DREV PROTEIN; 1.
DR   PANTHER; PTHR12890:SF0; PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE; 1.
DR   Pfam; PF05219; DREV; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EFO22517.2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095285};
KW   Transferase {ECO:0000313|EMBL:EFO22517.2}.
SQ   SEQUENCE   320 AA;  36585 MW;  7CA6EFADA4CBF902 CRC64;
     MFRTRGIARL LLEKEELDDR LLTSDHSEWY YIDRTAVTSY MLKKFHQFYM DEDVEEFLSN
     SLETSNSLCL QVCYALVTSL LSMVLTKTSI NGVLRRGGMH LFSFSQLQEF LDISAEWTFH
     DKKLLDLGAG DGQITAIMAR LYRTVSVTEA SKVMQWRLKQ RGFRVVPVDI WHQSGTYHLV
     SALNLLDRHY NPSLLLAQLH SITLRSKSLL LLAVVLPLHQ YVEFHPTSRT NRPDIKISIK
     GRTFEEQAGS LVADVLEPAG FELLKWGKLP YLSEGDVRRP FYHLDDAVFL LKPVNISSAG
     SSFSSILKNN SMSNRDFTSL
//