ID   A0A1I7VPB5_LOALO        Unreviewed;       570 AA.
AC   A0A1I7VPB5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=GATA zinc finger family protein {ECO:0000313|WBParaSite:EN70_4786};
GN   Name=LOAG_00900 {ECO:0000313|WBParaSite:EN70_4786};
OS   Loa loa (Eye worm) (Filaria loa).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX   NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_4786};
RN   [1] {ECO:0000313|Proteomes:UP000095285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Loa loa.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:EN70_4786}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A1I7VPB5; -.
DR   STRING; 7209.A0A1I7VPB5; -.
DR   WBParaSite; EN70_4786; EN70_4786; EN70_4786.
DR   eggNOG; KOG1601; Eukaryota.
DR   InParanoid; A0A1I7VPB5; -.
DR   Proteomes; UP000095285; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00202; ZnF_GATA; 1.
DR   Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR   InterPro; IPR039355; Transcription_factor_GATA.
DR   InterPro; IPR000679; Znf_GATA.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR10071:SF334; TRANSCRIPTION FACTOR ELT-2; 1.
DR   PANTHER; PTHR10071; TRANSCRIPTION FACTOR GATA FAMILY MEMBER; 1.
DR   Pfam; PF00320; GATA; 1.
DR   PRINTS; PR00619; GATAZNFINGER.
DR   SMART; SM00401; ZnF_GATA; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR   PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095285};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00094}.
FT   DOMAIN          363..417
FT                   /note="GATA-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50114"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          334..365
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          408..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..425
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        434..453
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   570 AA;  61963 MW;  53A2931E4D0582B6 CRC64;
     MEASQSWNGP GTSSAMKDTN AVAASHLSSF TQLPPSNNND ISKDNNNKDN GGKNSLSMSA
     PNSIKREIGA SLEANVMRRQ SVVVGPSSVI PNDGMSETKF HASNFSSLLP NLVQTPGMIF
     FCPDLPKNST QPFSELSTAV SCHHYPEWMG QSGVSLYPSC STAAAAALAT PQYYYAGVPS
     QAYLMQQTLG TELMPSTAIQ TYNTAVTATT QLSSSYDSFR MNTNYDPLSS YQLPQRTGMD
     GNLCVFPPQT LNGTIANSAI QPVTTSAQCQ QCGIYISDIA CSGTSTICTK CASDLMIHYS
     TTRPDMSQHI VSYSPFLNTS CGTAENNEQA LVSGQQQSIR INSSGSRNRQ LQRKNQPQHN
     SQRRQGLVCA NCRGTNTTLW RRDADGHPVC NACGLYFKLH QVQRPISMKK EGTLQTRKRK
     QKSDGILRQP VTSKKLGNHH NRGSRTYGSS NSASSLFSST VETVSDLVHP YNVISSVGSV
     NDDQLYAWNT GTQYDTSQEI SLSGLNANNV LSQSLFSTNH YDTTSGTEMI TTVGIPTEVI
     RRSEEEETTA AVHSLQVLKE ECVEPNDKFN
//