ID   A0A1I7VQ20_LOALO        Unreviewed;       322 AA.
AC   A0A1I7VQ20; A0A1S0TLJ0;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Sarcoglycan complex subunit protein {ECO:0000313|WBParaSite:EN70_501};
GN   ORFNames=LOAG_12266 {ECO:0000313|EMBL:EFO16242.1,
GN   ECO:0000313|WBParaSite:EN70_501};
OS   Loa loa (Eye worm) (Filaria loa).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX   NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_501};
RN   [1] {ECO:0000313|EMBL:EFO16242.1, ECO:0000313|Proteomes:UP000095285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Loa loa.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:EN70_501}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC       {ECO:0000256|ARBA:ARBA00004274}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004274}.
CC   -!- SIMILARITY: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
CC       {ECO:0000256|ARBA:ARBA00007574}.
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DR   EMBL; JH712075; EFO16242.1; -; Genomic_DNA.
DR   RefSeq; XP_003147828.1; XM_003147780.1.
DR   STRING; 7209.A0A1I7VQ20; -.
DR   EnsemblMetazoa; EFO16242.1; EFO16242.1; LOAG_12266.
DR   WBParaSite; EN70_501; EN70_501; EN70_501.
DR   eggNOG; KOG3950; Eukaryota.
DR   OMA; CLYCFIC; -.
DR   OrthoDB; 2913504at2759; -.
DR   Proteomes; UP000095285; Unassembled WGS sequence.
DR   GO; GO:0016012; C:sarcoglycan complex; IEA:InterPro.
DR   GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006875; Sarcoglycan.
DR   InterPro; IPR039972; Sarcoglycan_gamma/delta/zeta.
DR   PANTHER; PTHR12939:SF10; EG:4F1.1 PROTEIN; 1.
DR   PANTHER; PTHR12939; SARCOGLYCAN; 1.
DR   Pfam; PF04790; Sarcoglycan_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095285};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        71..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   322 AA;  35555 MW;  0F9ED0F9ACDCAA92 CRC64;
     MNTDVTSRLP LYQRTAEPVW GRSGYDFHRS PPPLQGATVP PYSTAVIHSA VKPPTESDIY
     RVGVYGWRKR CLYCFICALT VAVLLNLALT VWIMSVLDIS TTGMGTMRIE DDSIRVMGEA
     QFDLPVHFAE LSTADNEALT IDSYRGVFIK ARNMSGYQTA MLNMFQDGRM EAVCDRFEIY
     DNSRKLLFFA ESNEIGLKLE NLRILDDGGS VFEGAIQTAL IRPESDSPLS LESPTRSLYL
     EAGQDIEIIS AAGEIQLSSL LDITINSKQG EVRLESNSIV MSGLPRSEAR GSAQYQLCMC
     QNGLLFMAVV GADCRADRGI CS
//