ID   A0A1I7VT91_LOALO        Unreviewed;       283 AA.
AC   A0A1I7VT91; A0A1S0UBE1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=DNA/pantothenate metabolism flavoprotein {ECO:0000313|EMBL:EFO27215.1, ECO:0000313|WBParaSite:EN70_6013};
GN   ORFNames=LOAG_01280 {ECO:0000313|EMBL:EFO27215.1,
GN   ECO:0000313|WBParaSite:EN70_6013};
OS   Loa loa (Eye worm) (Filaria loa).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX   NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_6013};
RN   [1] {ECO:0000313|EMBL:EFO27215.1, ECO:0000313|Proteomes:UP000095285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Loa loa.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:EN70_6013}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the PPC synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005703}.
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DR   EMBL; JH712080; EFO27215.1; -; Genomic_DNA.
DR   RefSeq; XP_003136867.1; XM_003136819.1.
DR   AlphaFoldDB; A0A1I7VT91; -.
DR   STRING; 7209.A0A1I7VT91; -.
DR   EnsemblMetazoa; EFO27215.1; EFO27215.1; LOAG_01280.
DR   GeneID; 9938654; -.
DR   KEGG; loa:LOAG_01280; -.
DR   WBParaSite; EN70_6013; EN70_6013; EN70_6013.
DR   CTD; 9938654; -.
DR   eggNOG; KOG2728; Eukaryota.
DR   InParanoid; A0A1I7VT91; -.
DR   OMA; LERYQHH; -.
DR   OrthoDB; 6287at2759; -.
DR   Proteomes; UP000095285; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.40.50.10300; CoaB-like; 1.
DR   InterPro; IPR035929; CoaB-like_sf.
DR   InterPro; IPR007085; DNA/pantothenate-metab_flavo_C.
DR   PANTHER; PTHR12290; CORNICHON-RELATED; 1.
DR   PANTHER; PTHR12290:SF2; PHOSPHOPANTOTHENATE--CYSTEINE LIGASE; 1.
DR   Pfam; PF04127; DFP; 2.
DR   SUPFAM; SSF102645; CoaB-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000095285}.
FT   DOMAIN          17..72
FT                   /note="DNA/pantothenate metabolism flavoprotein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04127"
FT   DOMAIN          137..235
FT                   /note="DNA/pantothenate metabolism flavoprotein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04127"
SQ   SEQUENCE   283 AA;  31978 MW;  9D753AB37B11C96B CRC64;
     MVSVDSLIDD FVRQNSRKLV LITSGGTRVP LEKKVVRYID NFSMGTRGAA SAEYFLMKGY
     AVIFFHRDNS LKPFRRKFCN LFDHLVVNNS GKIEVQNMPG LLEALTLNSE LSDRLLMISF
     VDVSAYLMTL EMICLRLRSL GSSLLIYLAA AVSDFYISEE NLPEHKIHSN QGSLQLSLNI
     VPKILQKLVR DIVPKAFVVS FKLETDETVL VSKARQALQN YGHQLVIGNI LDTRKERVIF
     VSNGDKEETI CLNDEQKAAG VEIEQSIVDK LVEMHDKLLL NIK
//