ID A0A1I7VZB7_LOALO Unreviewed; 378 AA.
AC A0A1I7VZB7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=B30.2/SPRY domain-containing protein {ECO:0000313|WBParaSite:EN70_7924};
OS Loa loa (Eye worm) (Filaria loa).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_7924};
RN [1] {ECO:0000313|Proteomes:UP000095285}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Loa loa.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:EN70_7924}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR AlphaFoldDB; A0A1I7VZB7; -.
DR STRING; 7209.A0A1I7VZB7; -.
DR WBParaSite; EN70_7924; EN70_7924; EN70_7924.
DR eggNOG; KOG4367; Eukaryota.
DR Proteomes; UP000095285; Unassembled WGS sequence.
DR CDD; cd00063; FN3; 1.
DR CDD; cd12889; SPRY_PRY_TRIM67_9; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF15; E3 UBIQUITIN-PROTEIN LIGASE TRIM9; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000095285}.
FT DOMAIN 39..98
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT DOMAIN 105..197
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 179..369
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 378 AA; 41676 MW; CF6AB5818F2E58FD CRC64;
MLPSGSIVGN RRIFKEQIGR CTTKLSKTTA LIQFCIEVLK EPDPATYLQV SSALINRATT
QEFLWHKEMQ TTPETDPDFI LNLDVNNLEY AIQTLDFAQL KAPNAPLIET AECVAENNSV
TIVWKAQNDD CAIDGYMLEI DSGSGDGLFK EVYCGRDTIC TIDGLHFNTV YNARVKAFNA
AGESSYSDII CLQTATVAWF QLSKSASQND LTVSNECMSL TGTTMEYRSL CGSIAFSRGT
HYWEITVERH TGNADVVVGV AQSAFNRHIM LGKDLHGWSM YIDGERSWYL HNGMHHSRII
GGIGVGSVIG VLLDCDKGTL AFFVNDTRRE YEGQLVAFRN MPRGLYYPAF SVNCDALITV
HTGLTIPSSS GSSDCSDT
//
