ID   A0A1I7W1P7_LOALO        Unreviewed;       326 AA.
AC   A0A1I7W1P7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Apple domain-containing protein {ECO:0000313|WBParaSite:EN70_8675};
OS   Loa loa (Eye worm) (Filaria loa).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
OX   NCBI_TaxID=7209 {ECO:0000313|Proteomes:UP000095285, ECO:0000313|WBParaSite:EN70_8675};
RN   [1] {ECO:0000313|Proteomes:UP000095285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Henn M.R.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Loa loa.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:EN70_8675}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   STRING; 7209.A0A1I7W1P7; -.
DR   WBParaSite; EN70_8675; EN70_8675; EN70_8675.
DR   Proteomes; UP000095285; Unassembled WGS sequence.
DR   CDD; cd01099; PAN_AP_HGF; 1.
DR   Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 1.
DR   InterPro; IPR003609; Pan_app.
DR   Pfam; PF00024; PAN_1; 1.
DR   SMART; SM00473; PAN_AP; 1.
DR   SUPFAM; SSF57414; Hairpin loop containing domain-like; 1.
DR   PROSITE; PS50948; PAN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000095285}.
FT   DOMAIN          14..96
FT                   /note="Apple"
FT                   /evidence="ECO:0000259|PROSITE:PS50948"
FT   REGION          187..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          306..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        187..237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        238..270
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   326 AA;  36886 MW;  D2816D065A0D364A CRC64;
     XTWFRLAPAT VLECFKYYPN YYLGKSGNLV VVNISSVNSC LDHCLKSQLL YEFICRSAMV
     NKIQRECILS KWSPDLAAFS RYQSKIVYTI FYQNICLPPW NQIQNFTIAP PRTTFPMPIS
     NTRLPLPNSI NNMNKNYKSI NNAHDITVNP ENKKKSSFEM ALDNARHVPP PNTINPIIIH
     RFVKSTGTTI PPDQKTTSYY INYDDEGSNS NGDNKDCDNN NNNNHGDDIN DGGNNNNSDN
     GDDDDDDDGD DDNDNIYNNN EYDDNEESSD LTSHDEYHTT ANKDIAYRIA ASLLTPVRTI
     KSAAIRPGPV STHRNFQQRS EAPIAK
//