ID   A0A1I7WJD0_HETBA        Unreviewed;       183 AA.
AC   A0A1I7WJD0;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=3Beta_HSD domain-containing protein {ECO:0000313|WBParaSite:Hba_05074};
OS   Heterorhabditis bacteriophora (Entomopathogenic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Heterorhabditidae;
OC   Heterorhabditis.
OX   NCBI_TaxID=37862 {ECO:0000313|Proteomes:UP000095283, ECO:0000313|WBParaSite:Hba_05074};
RN   [1] {ECO:0000313|WBParaSite:Hba_05074}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I7WJD0; -.
DR   WBParaSite; Hba_05074; Hba_05074; Hba_05074.
DR   Proteomes; UP000095283; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        158..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          33..91
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   183 AA;  20685 MW;  8E59DBB7F2933538 CRC64;
     MRVCIVGGGG YLGQHVAKHL QADDHHTVLL DISYVDVNKK MIFKINVDGT RLLMHSCRKL
     GVRRFIFASS VGVIFTDKKL VMVNEDEPYP PESAVSLFTY FLEKLLYNGP ALTQYSGIHN
     CSQAMVLAEK ELRKVKPRCA GKMVQYYQQH FDTNPRSMID FFSIFKITLA CILFTLVIIS
     SSG
//