ID A0A1I7X9G6_HETBA Unreviewed; 342 AA.
AC A0A1I7X9G6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Nuclear receptor {ECO:0000313|WBParaSite:Hba_14226};
OS Heterorhabditis bacteriophora (Entomopathogenic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heterorhabditidae;
OC Heterorhabditis.
OX NCBI_TaxID=37862 {ECO:0000313|Proteomes:UP000095283, ECO:0000313|WBParaSite:Hba_14226};
RN [1] {ECO:0000313|WBParaSite:Hba_14226}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR AlphaFoldDB; A0A1I7X9G6; -.
DR WBParaSite; Hba_14226; Hba_14226; Hba_14226.
DR Proteomes; UP000095283; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46011:SF6; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-86; 1.
DR PANTHER; PTHR46011; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-86-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 1..342
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT DOMAIN 3..40
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
SQ SEQUENCE 342 AA; 39565 MW; C62DA80867E28D60 CRC64;
MEERLCRVCA DLSDGAHFGI DSCRACAAFF RRSVVMRKRY PGVQNRRDPI IPRRSEPDSI
SIASLHLDGP SESGLTQDPF AGGIQSDNSQ SSSVKPQDLP LFLYNINDSY KKLCAERKRT
ELSMNVSSLK EIFEPPAIWQ WIIFHSFVIT LWGMDSAYRT YKMIPPEQCN TKKIITETTY
IDLDNIDAFF SDGPTSKLSK EHLTNLMRNC IKRTQTSVID KMRELQITDE EFAALLSLSL
WNTNLSNGNE KIETIAKRMR AKIFHELHLL YRYVSSIAYV KSEIYFHFRY ENLDEYAGRL
GELMILLCSV QYDVSRMKED MELFNLLDVF SRDSFLYDII KG
//
