ID   A0A1I7XGH8_HETBA        Unreviewed;       214 AA.
AC   A0A1I7XGH8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=HECT domain-containing protein {ECO:0000313|WBParaSite:Hba_16587};
OS   Heterorhabditis bacteriophora (Entomopathogenic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Heterorhabditidae;
OC   Heterorhabditis.
OX   NCBI_TaxID=37862 {ECO:0000313|Proteomes:UP000095283, ECO:0000313|WBParaSite:Hba_16587};
RN   [1] {ECO:0000313|WBParaSite:Hba_16587}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
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DR   AlphaFoldDB; A0A1I7XGH8; -.
DR   WBParaSite; Hba_16587; Hba_16587; Hba_16587.
DR   Proteomes; UP000095283; Unplaced.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR000569; HECT_dom.
DR   InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR43975; ZGC:101858; 1.
DR   PANTHER; PTHR43975:SF2; ZGC:101858; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   Pfam; PF00632; HECT; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS50237; HECT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW   ECO:0000256|PROSITE-ProRule:PRU00104}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..214
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009311240"
FT   DOMAIN          133..208
FT                   /note="HECT"
FT                   /evidence="ECO:0000259|PROSITE:PS50237"
SQ   SEQUENCE   214 AA;  23287 MW;  697185C1D4572091 CRC64;
     MLGLFGFLSH IYLGASSGIG HGAAIKMAKE GYALSLSGRN EEALMAVARE CSELGVGDNH
     VNSAGILTSG PVIDTDINVY DKQMDVNVRR CVLIHFINFF SVVQLTRLVL PHLINTKGTV
     VNVSSITGPC PVLLDQQPTL EDLCELSPVE GRSLQELLDY QGDDFEDVFC LTFTFSCTAL
     GQTETVDLKT EGSKITVTQL NKNEYVQIHS TVYP
//