ID A0A1I7XS45_HETBA Unreviewed; 641 AA.
AC A0A1I7XS45;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=PHB domain-containing protein {ECO:0000313|WBParaSite:Hba_20308};
OS Heterorhabditis bacteriophora (Entomopathogenic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heterorhabditidae;
OC Heterorhabditis.
OX NCBI_TaxID=37862 {ECO:0000313|Proteomes:UP000095283, ECO:0000313|WBParaSite:Hba_20308};
RN [1] {ECO:0000313|WBParaSite:Hba_20308}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
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DR AlphaFoldDB; A0A1I7XS45; -.
DR WBParaSite; Hba_20308; Hba_20308; Hba_20308.
DR Proteomes; UP000095283; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd03406; SPFH_like_u3; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR033294; Erlin1/2.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR15351:SF3; ERLIN; 1.
DR PANTHER; PTHR15351; ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG; 1.
DR Pfam; PF01145; Band_7; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REPEAT 14..106
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 118..225
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 234..329
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT DOMAIN 324..490
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
SQ SEQUENCE 641 AA; 72089 MW; 59200AA133F3A237 CRC64;
MVGYNPEPIN GKDLSSVEYS EAGLASGVAT RVIVQPLDVI KIRFQLQEEP IRGNKSGKYK
GVFQSMHVII REEGLKAFWK GHVPAQGLSA MYGVVQFASF EFLSREVGNH LSYVHPSVRS
TVDFACGGLS GCLAMTAAMP LDVIRTRLVA QSGKALYKGI CTKNITHIER LEFIYFCLIG
TFHAISHIWQ KEGIIGYFRG WAPSLVQIAP FTGLQFALYN FFMELWPQFV VTDHDSTGAL
VSGALAGTVA KTALYPLDMV RHRLQMNGFD RHGFGRTSDY RKGMFRTIVM VVRNESIYGL
FKGPRMIPQG LIIVFAVTSL FMFTSLHHIE EGHVGVYFRG GALLSRVSQP GYHLMIPFVT
SYRSVQVTLQ TDEAKNVPCG TSGGVMIYFD RIEVVNILSA GSVYDIVKNY TVDYDKPLIF
NKVHHEVNQF CSSHSLQEVY IDLFDQIDEN LKTALQEDLT VMAPGLFVQA VRVTKPKIPE
AIRHNYEQME AEKTKLLVAT QHQKVVEKEA ETERKKAVIE AEKKAQVAAI MHKQTIAEKE
TQKKICQLED ESHLGKYNLP IVISQKAKAD ADHYRAQKEA ESNRLLLTKE YLELKRIEAI
AKNNKIYYGQ DIPNVFFQAD EATQLLSVDV PNMAGKQKRD L
//
