ID A0A1I7Y5W3_9BILA Unreviewed; 512 AA.
AC A0A1I7Y5W3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=ShKT domain-containing protein {ECO:0000313|WBParaSite:L893_g12988.t1};
OS Steinernema glaseri.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC Steinernema.
OX NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g12988.t1};
RN [1] {ECO:0000313|WBParaSite:L893_g12988.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01005}.
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DR AlphaFoldDB; A0A1I7Y5W3; -.
DR WBParaSite; L893_g12988.t1; L893_g12988.t1; L893_g12988.
DR Proteomes; UP000095287; Unplaced.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR InterPro; IPR003582; ShKT_dom.
DR PANTHER; PTHR11475:SF4; LD42267P; 1.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR Pfam; PF01549; ShK; 1.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SMART; SM00254; ShKT; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
DR PROSITE; PS51670; SHKT; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU01005};
KW Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..512
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009311737"
FT DOMAIN 27..61
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT BINDING 404
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
FT DISULFID 27..61
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01005"
SQ SEQUENCE 512 AA; 57591 MW; D1330D681147C86E CRC64;
MWNVQALLLL GFLAIITGAE LQCIGSCCDK DEQCFKRAES GECAERPGWM LRNCPASCGL
CPEQSKCPSV HTIEDGLRHR MTKNKFVNQF QMSQCAPLNQ PTDCKLNMCY HLKFRSFDGA
CNNLHMSLLG AAYRPFKRLL SPNYDDRVNA ATGSLMRILP NPRDVTLHLL RSGRSPTVRP
NSLFMQWGQF LAHDMTANGL DNKCQCGSND RIRCANIKST RERRCISFTR SIPACGTGIR
GDPREQVNRN TPFIDASVVY GSDHTMVKSL RKGLSGFLRD MKATHDHKRG HSFPPLPSET
TFSVGDDRSN VFFGLGAFHT IFLRLHNKIA KQLKSINPGW DGERLFQETR KIVGAYMQVI
TYQEFLPALL GDDVDSLIPP YSGYKPTVDP AVANEFAGAA FRLHGLIMPS FPSLDHRWHK
YEENQFSAMQ LNDSRVVDGG TDDLIRGMMS TPSRAPQTIS LQVTEKAFGG LVDLASINIQ
RGRDHGFQPY NEYRRKVCNL PPVWSFSKWR GL
//
