ID   A0A1I7YLR7_9BILA        Unreviewed;       320 AA.
AC   A0A1I7YLR7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=glucose-6-phosphate dehydrogenase (NADP(+)) {ECO:0000256|ARBA:ARBA00013019};
DE            EC=1.1.1.49 {ECO:0000256|ARBA:ARBA00013019};
OS   Steinernema glaseri.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC   Steinernema.
OX   NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g17404.t1};
RN   [1] {ECO:0000313|WBParaSite:L893_g17404.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-
CC         lactone + H(+) + NADPH; Xref=Rhea:RHEA:15841, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:57955, ChEBI:CHEBI:58349,
CC         ChEBI:CHEBI:61548; EC=1.1.1.49;
CC         Evidence={ECO:0000256|ARBA:ARBA00001220};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:15842;
CC         Evidence={ECO:0000256|ARBA:ARBA00001220};
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC       {ECO:0000256|ARBA:ARBA00004959}.
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DR   AlphaFoldDB; A0A1I7YLR7; -.
DR   WBParaSite; L893_g17404.t1; L893_g17404.t1; L893_g17404.
DR   Proteomes; UP000095287; Unplaced.
DR   GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:InterPro.
DR   InterPro; IPR001282; G6P_DH.
DR   InterPro; IPR022675; G6P_DH_C.
DR   PANTHER; PTHR23429:SF0; GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE; 1.
DR   PANTHER; PTHR23429; GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD; 1.
DR   Pfam; PF02781; G6PD_C; 1.
DR   PRINTS; PR00079; G6PDHDRGNASE.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
PE   4: Predicted;
FT   DOMAIN          58..316
FT                   /note="Glucose-6-phosphate dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02781"
SQ   SEQUENCE   320 AA;  36312 MW;  F142F153860454B6 CRC64;
     MEQPITTYHG STTPVIIVTF GPANRLFYLA LPPQLVQSVS TRIKMHCMTS KGCPPLFAAW
     NRNRVDYVVI SFKEDCEAQP GEFDKSGIIR EVMQNHLMQV LTLVAMEMPR SLQGEDLRDE
     KVKVLKSIAP VTVDDVVLGR YVGNPHSYHP EAAVGYLDED GVPKDSGTPT YALAVLHVNN
     ERWHGVPFFL RCGKGLNERK AEVRIDFYEL EEDVAQNGGS DRNEVSIKCH PTEAVYFTTS
     GGFHWGIRLP DAYERLFLEV INGSQINFVR TDELDYAWKI FTPLLKKIER EEITPKRYLF
     GSRGPQEADL LMKKYGVPLF
//