ID   A0A1I7ZCW3_9BILA        Unreviewed;       327 AA.
AC   A0A1I7ZCW3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog {ECO:0000256|HAMAP-Rule:MF_03037};
OS   Steinernema glaseri.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC   Steinernema.
OX   NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g25132.t1};
RN   [1] {ECO:0000313|WBParaSite:L893_g25132.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000256|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000256|HAMAP-
CC       Rule:MF_03037}.
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DR   AlphaFoldDB; A0A1I7ZCW3; -.
DR   WBParaSite; L893_g25132.t1; L893_g25132.t1; L893_g25132.
DR   Proteomes; UP000095287; Unplaced.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR024977; Apc4-like_WD40_dom.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19920:SF0; CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED; 1.
DR   PANTHER; PTHR19920; WD40 PROTEIN CIAO1; 1.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 5.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          58..99
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          102..143
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          147..188
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          192..224
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          257..324
FT                   /note="Anaphase-promoting complex subunit 4-like WD40"
FT                   /evidence="ECO:0000259|Pfam:PF12894"
SQ   SEQUENCE   327 AA;  37289 MW;  78B2C388FC31B5FD CRC64;
     MGSLKQVARL EHSSDVGAER TWSVRWNHNG VLLGSCGENK SLRIWRRSSE KFELLTTLKD
     HERAVRYLDF SPCGNYVASV GFDAVIIVYQ FENGDFEEVT RMEGHENEVK CCTFSPSGRF
     LASCSRDKSV WFWQMDEDDD FQVCSILQPH TGDVKFVTWH PSEEVLVSCS YDASIKFYRF
     DGEDWVTQQR IENAHESTVW SAAFDAEGNY LATVGADHRV NVWKRIFDDS TTSVASSSWK
     KVVEYDVPNC IWPLYSVSWN HFNDMIAVGG GDSRVRLIQF DRQSETVTEV FSLKVDDEVN
     SVAWNPKEPT LLATGTDDGF VTVFELC
//